Skip to main content
SpringerLink
Log in

The effect of extracorporeal electromagnetic shock waves on renal proximal tubular function

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

In order to investigate the effect of electromagnetic shock waves on proximal tubular renal function, we measured the urine levels of the lysosomal enzyme N-acetyl-beta-glucosaminidase (NAG) prior to, 1 hour, 1 day, and 1 week after extracorporeal electromagnetic lithotripsy (ESWL) in 50 patients with urinary stone disease. Mean NAG level which was 5.18+0.09 U/l prior to ESWL increased to 5.29+0.09 U/l in the first hour and to 10.7+0.19 U/l on the first day after ESWL (p<0.001). The level returned to pre-ESWL values one week after ESWL (5.27+0.09 U/l).

These findings show that extracorporeal electromagnetic shock waves cause significant damage to the proximal tubular epithelium of the kidney; however, these changes return to normal in the first week.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Lingemann, J. E., Smith, L. H., Woods, J. R., Newman, D. M.: Bioeffects and long term results of ESWL in urinary calculi. In: ESWL, Endourology and Medical Therapy. Lea and Febiger, Philadelphia 1989, Chapter 36, pp. 273–292.

    Google Scholar 

  2. Lingemann, J. E., Woods, J., Toth, P. D., Evan, A. P., McAteer, J. A.: The role of lithotripsy and its side effects.J. Urol., 141, 793 (1989).

    Google Scholar 

  3. Baumgartner, B. R., Dickey, K. W., Ambrose, S. S., Walton, K. N., Nelson, R. C., Bernardino, M. E.: Kidney changes after extracorporeal shock wave lithotripsy—appearance on MRI imaging.Radiology, 163, 531 (1987).

    PubMed  CAS  Google Scholar 

  4. Tataranni, G., Farinelli, R., Zavagli, G., Logallo, G., Farinelli, A.: Tubule recovery after obstructive nephropathy relief: The value of enzymuria and microproteinuria.J. Urol., 138, 24 (1987).

    PubMed  CAS  Google Scholar 

  5. Kishimoto, T., Yamamoto, K., Sugimoto, T., Komamoto, S.: Side effects of extracorporeal shock wave exposure in patients treated by extracorporeal shock wave lithotripsy for upper urinary tract stone.Eur. Urol., 12, 308 (1986).

    PubMed  CAS  Google Scholar 

  6. Trinchieri, A., Zanetti, G., Tombolini, P., Mandressi, A.: Urinary NAG excretion after anaesthesia-free extracorporeal lithotripsy of renal stones: A marker of early tubular damage.Urol. Res., 18, 259 (1990).

    Article  PubMed  CAS  Google Scholar 

  7. Karlsen, S. J., Berg, K. J.: Acute changes in kidney function following extracorporeal shock wave lithotripsy for renal stones.Br. J. Urol., 67, 241 (1991).

    Article  PubMed  CAS  Google Scholar 

  8. Ruiz Marcellan, F. J., Ibarz Servio, L.: Evaluation of renal damage in extracorporeal lithotripsy by shock waves.Eur. Urol., 12, 73 (1986).

    PubMed  CAS  Google Scholar 

  9. Trinchieri, A., Mandressi, A., Zanetti, G., Tombolini, P.: Renal tubular damage after renal stone treatment.Urol. Res., 16, 101 (1988).

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Urology and Biochemistry, Dokuz Eylül University, School of Medicine, Inciralti, Izmir, Turkey

    Z. Kirkali, G. Kirkali & Y. Tahiri

Authors
  1. Z. Kirkali
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Kirkali
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Y. Tahiri
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kirkali, Z., Kirkali, G. & Tahiri, Y. The effect of extracorporeal electromagnetic shock waves on renal proximal tubular function. Int Urol Nephrol 26, 255–257 (1994). https://doi.org/10.1007/BF02768206

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02768206

Keywords

Search

Navigation