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Cold adaptation modulates Ca2+ signaling in brown preadipocytes

  • Biophysics And Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

One-week cold exposure of mice led to a 2-fold increase in the density of α1-adrenoceptors in brown adipose tissue. The density of α1-adrenoceptors returned to normal after adaptation to cold for 2 weeks. The reduced Ca2+ signaling in stem cells of brown fat activated via β-adrenoceptors and cAMP was transformed into the Ca2+-system induced by α1-adrenoceptors and similar to that in mature brown adipocytes.

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Authors and Affiliations

  1. Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino

    A. S. Baumuratov, B. B. Abzhalelov, L. I. Kramarova, L. P. Dolgacheva, V. P. Zinchenko & G. E. Bronnikov

  2. Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino

    L. I. Kramarova

Authors
  1. A. S. Baumuratov
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  2. B. B. Abzhalelov
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  3. L. I. Kramarova
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  4. L. P. Dolgacheva
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  5. V. P. Zinchenko
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  6. G. E. Bronnikov
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Corresponding author

Correspondence to L. P. Dolgacheva.

Additional information

Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 138, No. 7, pp. 59–62, July, 2004

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Baumuratov, A.S., Abzhalelov, B.B., Kramarova, L.I. et al. Cold adaptation modulates Ca2+ signaling in brown preadipocytes. Bull Exp Biol Med 138, 50–53 (2004). https://doi.org/10.1007/BF02694473

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  • DOI: https://doi.org/10.1007/BF02694473

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