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Dose response of rat brains interstitially irradiated by argon laser light

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Abstract

The dose-response curve is reported of healthy rat brains exposed interstitially to argon laser light. By means of a 0.4 mm diameter optical fibre, doses of 1 W and 0.25 W were administered, for periods from 0 to 60 s. Well circumscribed oval lesions were obtained, sometimes with unexpected extensions towards a ventricle and even at distances from the main lesion.

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References

  1. Salcman M. Survival in glioblastoma: Historical perspective.Neurosurgery 1980,7:435–9.

    Article  PubMed  CAS  Google Scholar 

  2. Kelly PJ, Kall BA, Goerss S, Earnest IV F. Computer-assisted stereotaxic laser resection of intra-axial brain neoplasms.J Neurosurg 1986,64:427–39

    Article  PubMed  CAS  Google Scholar 

  3. Rijn J van, Berg J van den, Schamhart DHJ, Wijk R van. Effect of Thermotolerance on thermal radiosensitization in Hepatoma cells.Radiat Res 1984,97:318–28

    Article  PubMed  Google Scholar 

  4. Selker RG. Hyperthermia in the treatment of intracranial tumours. In: Wilkins RH, Rengachary SS (eds)Neurosurgery, New York: McGraw Hill, 1985:2724

    Google Scholar 

  5. Storm FK, Harrison WH, Elliot RS, Morton DL. Normal tissue and solid tumor effects of hyperthermia in animal models and clinical trials.Cancer Res 1979,39:2245–51

    PubMed  CAS  Google Scholar 

  6. Hahn GM.Hyperthermia and cancer. New York: Plenum Press, 1982:285

    Google Scholar 

  7. Bleehen NM. Hyperthermia in the treatment of cancer.Br J Cancer, Suppl V, 1982, 96–100

    Google Scholar 

  8. Svaasand LO, Ellingsen R. Optical properties of human brain.Photochem Photobiol 1983,38:293–9

    PubMed  CAS  Google Scholar 

  9. Matthewson K, Coleridge-Smith P, O’Sullivan JP et al. Biological effects of intra-hepatic Nd-YAG Laser photocoagulation in rats.Gastroenterology (in press)

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Authors and Affiliations

  1. Department of Neurosurgery, Faculty of Medicine and Free University Hospital, Amsterdam

    J. G. Wolbers

  2. Division of Neuropathology, Department of Pathology, Faculty of Medicine, Free University, Amsterdam

    W. Kamphorst

  3. Laser Application and Information Centre Amsterdam (LAICA), Department of Physics, Free University, Amsterdam

    H. J. C. M. Sterenborg & W. Hogervorst

  4. LAICA, Department of Physics, Free University, Amsterdam

    M. J. C. Van Gemert

  5. St Joseph Hospital, Eindhoven

    M. J. C. Van Gemert

Authors
  1. J. G. Wolbers
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  2. W. Kamphorst
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  3. H. J. C. M. Sterenborg
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  4. M. J. C. Van Gemert
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  5. W. Hogervorst
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Wolbers, J.G., Kamphorst, W., Sterenborg, H.J.C.M. et al. Dose response of rat brains interstitially irradiated by argon laser light. Laser Med Sci 2, 255–260 (1987). https://doi.org/10.1007/BF02594169

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  • DOI: https://doi.org/10.1007/BF02594169

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