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Laser angioplasty of arterial stenoses

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Abstract

To establish the optimal conditions for recanalization of obstructed arteries without damage to vessel walls, an Nd-YAG laser coupled to a 0.2-mm-diameter optical fiber was used on obstructed human cadaver coronary and peripheral arteries and on poplitieal arteries in amputated limbs. Vaporization of atheromatous plaques was consistently obtained with energy of 360–600 J and a diluted blood perfusate (3 g/100 ml hemoglobin) at a rate of 30 ml/min. The arterial wall was protected from thermal injury by inserting the optical fiber into an inflated balloon catheter and by cooling the system with the perfusate. Since recanalization of occluded arteries was consistently obtained without damage to the arterial wall or debris and thin and flexible optical fibers were easy to guide in the arteries, percutaneous transluminal Nd-YAG laser angioplasty was used in obstructed femoral and popliteal arteries in 12 patients. The first trials in man with Nd-YAG laser showed the method to be feasible, effective, and at low risk, although further studies are required to improve penetration of the obstruction and increase the diameter tunnel.

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Authors and Affiliations

  1. Department of Clinical Investigation, University Hospital Henri Mondor, Creteil, France

    Herbert J. Geschwind M.D., Bernard Teisseire, Georges Boussignac & Christian Vieilledent

  2. Division of Cardiology, St. Louis University Medical School, 1325 South Grand Boulevard, 63104, St. Louis, MO, USA

    Herbert J. Geschwind M.D., Bernard Teisseire, Georges Boussignac & Christian Vieilledent

Authors
  1. Herbert J. Geschwind M.D.
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  2. Bernard Teisseire
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  3. Georges Boussignac
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  4. Christian Vieilledent
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Geschwind, H.J., Teisseire, B., Boussignac, G. et al. Laser angioplasty of arterial stenoses. Cardiovasc Intervent Radiol 9, 313–317 (1986). https://doi.org/10.1007/BF02577962

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  • DOI: https://doi.org/10.1007/BF02577962

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