Abstract
A genetic polymorphism of β-chain rabbit (Oryctolagus cuniculus) hemoglobin is demonstrated by means of acid starch gel electrophoresis. The biochemical evidence presented suggests that a previously reported substitution of a neutral amino acid for a histidine is responsible for the detected genetic variation. Segregation analysis was performed in a sample of 15 matings with 49 offspring and confirmed the genetic hypothesis: two common alleles at an autosomal locus. The calculated gene frequencies in a random sample of 125 individuals areHBB*1=0.48 andHBB*2=0.52.
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Ferrand, N. Biochemical and genetic studies on rabbit hemoglobin. I. Electrophoretic polymorphism of theβ chain. Biochem Genet 27, 673–678 (1989). https://doi.org/10.1007/BF02396059
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DOI: https://doi.org/10.1007/BF02396059