Abstract
We present a 5-year-old boy with a severe form of X-linked chronic granulomatous disease and hypersensitivity to sulphamides preventing prophylaxis with trimethoprim-sulphomethoxazole. Bone marrow transplantation was performed after preconditioning with busulphan and cyclophosphamide. The immediate post-transplant period was with-out complications. Complete chimerism was demonstrated and post-transplant oxidative metabolism was normal. The patient is asymptomatic 30 months after the graft.
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Abbreviations
- BMT :
-
bone marrow transplantation
- CGD :
-
chronic granulomatous disease
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Calviño, M.C., Maldonado, M.S., Otheo, E. et al. Bone marrow transplantation in chronic granulomatous disease. Eur J Pediatr 155, 877–879 (1996). https://doi.org/10.1007/BF02282837
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DOI: https://doi.org/10.1007/BF02282837