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Synthesis and biological activity of yuccagenin bisrhamnoside

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Abstract

The two hydroxyls of yuccagenin can be glycosylated by Koenigs-Knorr condensation with acetobromorhammose in dichloroethane in the presence of mercuric cyanide. The bisrhamnoside of yuccagenin markedly lowers the cholesterol and triglyceride content in blood serum of healthy animals and animals with experimental hyperlipidemia.

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References

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Authors and Affiliations

  1. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    Z. A. Khushbaktova & V. N. Syrov

  2. Pharmaceutical Institute, pr. Aibeka, 45, Tashkent-15

    N. Sh. Pal'yants, E. A. Pshenichnov & A. K. Karimov

Authors
  1. N. Sh. Pal'yants
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  2. Z. A. Khushbaktova
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  3. E. A. Pshenichnov
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  4. V. N. Syrov
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  5. A. K. Karimov
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Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 242–243, May–June, 2000.

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Pal'yants, N.S., Khushbaktova, Z.A., Pshenichnov, E.A. et al. Synthesis and biological activity of yuccagenin bisrhamnoside. Chem Nat Compd 36, 299–301 (2000). https://doi.org/10.1007/BF02238341

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  • DOI: https://doi.org/10.1007/BF02238341

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