Abstract
We report 7 cases of acute polyneuropathy fitting the NINDS diagnostic criteria for GBS. Electrophysiological study and sural nerve biopsy revealed a picture of axonal polyneuropathy, without changes suggesting demyelination. We discuss whether the acute idiopathic axonal neuropathy belongs to the GBS spectrum or represents a separate clinico-pathological entity.
Sommario
Descriviamo 7 casi di polineuropatia acuta che soddisfano i criteri diagnostici del NINDS (3). Lo studio elettrofisiologico e la biopsia di nervo surale (eseguita in due pazienti) hanno evidenziato un quadro di neuropatia con evidenti fenomeni di degenerazione assonale, ma senza segni di demielinizzazione. discutiamo se la neuropatia acuta assonale idiopatica appartiene allo spettro della sindrome di Guillain-Barré o costituisce una diversa entità clinico-patologica.
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Magi, S., Sabatelli, M., Mignogna, T. et al. Acute axonal idiopathic polyneuropathy: A Guillain-Barré syndrome variant?. Ital J Neuro Sci 13, 481–486 (1992). https://doi.org/10.1007/BF02230868
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DOI: https://doi.org/10.1007/BF02230868