Abstract
We report a case of neuroleptic malignant syndrome (NMS) following abrupt reducation of chronic levodopa treatment in a 71 year old female parkinsonian patient. The NMS resolved within 24 hours of the addition of apomorphine to levodopa therapy.
Sommario
Si riporta un caso di sindrome maligna insorta in una donna di 71 anni affetta da morbo di Parkinson, dopo brusca riduzione della terapia cronica con levodopa e rapidamente risolta dal trattamento combinato con levodopa e apomorfina.
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References
Figà-Talamanca L., Gualandi G., Di Meo L., Di Battista G., Neri G., Lo Russo F.:Hyperthermia after discontinuance of levodopa and bromocriptine therapy: impaired dopamine receptors as possible cause Neurology 35:258–261, 1985.
Friedman J.H., Feinberg S.S., Feldman R.G.:A neuroleptic malignant like syndrome due to levodopa therapy withdrawal. JAMA 254:2792–2795, 1985.
Luquin M.R., Lera G., Delgado G., Salazar J.M., Obeso J.A.:Neuroleptic malignant syndrome treated with subcutaneous lisuride infusion. Movement Disorders, 5:170–172, 1990
Rosenberg M.R., Green M.:Neuroleptic malignant syndrome. Review of response to therapy. Arch Intern Med 149:1927–1931, 1989
Sechi G.P., Tanda F., Mutani R.:Fatal hyperpyrexia after withdrawal of levodopa. Neurology 34:249–251, 1984.
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Bonuccelli, U., Piccini, P., Corsini, G.U. et al. Apomorphine in malignant syndrome due to levodopa withdrawal. Ital J Neuro Sci 13, 169–170 (1992). https://doi.org/10.1007/BF02226968
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DOI: https://doi.org/10.1007/BF02226968