Skip to main content
Log in

Blei-, Cadmium-, Chrom-, Mangan- und Zinkgehalt atherosklerotisch veränderter menschlicher Aorten

  • Originalarbeiten / Original Works
  • Published:
Zeitschrift für Rechtsmedizin Aims and scope Submit manuscript

Summary

The contents of lead, cadmium, chromium, manganese, and zinc of 30 atherosclerotic aortas of deceased males between the age of 44 and 73 was analysed with flameless atomic absorption spectroscopy according to the localisation within the aorta (Arcus aortae, Aorta thoracalis, Aorta lumbalis). Furthermore, the metal concentration according to the degree of atherosclerosis was determined whereas, contrary to other authors, no significant relationship between metal content and grade of atherosclerosis was found.

A correlation between heavy metal content of atherosclerotic and non-atherosclerotic aortas could not be ascertained statistically. Likewise, no significant relationship between calcium concentration and content of heavy metals was verified.

Zusammenfassung

Der Blei-, Cadmium-, Chrom-, Mangan- und Zinkgehalt von 30 in unterschiedlichem Maße arteriosklerotisch veränderter Aorten männlicher Verstorbener im Altersbereich von 44–75 Jahren wurde mittels flammenloser Atom-Absorptions-Spektrophotometrie in Abhängigkeit von der Lokalisation innerhalb des Gefäßes (Arcus aortae, Aorta thoracalis, Aorta lumbalis) bestimmt.

Weiterhin wurde der Metallgehalt in Abhängigkeit von dem Grad der Atherosklerose uhtersucht, wobei im Gegensatz zu anderen Autoren keine statistisch signifikante Zunahme des Metallgehaltes bei höherem Grad atherosklerotischer Wandveränderung gefunden wurde.

Ein statistisch gesicherter Unterschied zwischen dem Schwermetallgehalt atherosklerosefreier und atherosklerotischer Aorten besteht nicht.

Ein signifikanter Zusammenhang zwischen der Ca- und der Schwermetall-konzentration atherosklerotisch veränderter Aorten wurde nicht gefunden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  • Bala JM, Plotko SA (1967) Ateroskleros i mikroslementij. In: Trudy IV Vsesoiuz S'ezda Patol Anat Kischinew, Isdatelwstwo Med, Moskwa

    Google Scholar 

  • Barry PSI (1975) A comparison of concentrations of lead in human tissues. Br J Industr Med 32: 119–139

    Google Scholar 

  • Blumenthal HT, Lansing AI, Wheeler TA (1944) Calcification of media of human aorta and its relation to intimal atherosclerosis, ageing, and disease. Am J Pathol 20: 665–687

    Google Scholar 

  • Burch RE, Sullivan JF (1976) Clinical and nutritional aspects of zinc deficiency and excess. Med Clin N Am 60: 675–685

    PubMed  Google Scholar 

  • Drescher S (1969) Zur Hemmwirkung von Metallsalzen auf die experimentelle Gefäßcalcinose. Beitr Pathol Anat 139: 74–92

    PubMed  Google Scholar 

  • Klevay LM (1977) Elements of ischemic heart disease. Perspect Biol Med (2) 20: 186–192

    PubMed  Google Scholar 

  • Kottke BA, Subbiah MTR (1978) Pathogenesis of atherosclerosis. Concepts based on animal models. Mayo Clin Proc 53: 35–48

    PubMed  Google Scholar 

  • Masironi R (1969) Trace elements and cardiovascular diseases. Bull WHO 40: 305–312

    PubMed  Google Scholar 

  • Masironi R, Miesch AT, Crawford MD, Hamilton El (1972) Geochemical environments, trace elements, and cardiovascular diseases. Bull WHO 47: 139–150

    PubMed  Google Scholar 

  • Morris JN, Crawford MD, Heady JA (1963) zit bei Sharrett AR (1977)

  • Neri LC, Hewitt D, Schreiber G (1974) Can epidemiology elucidate the water story? Am J Epidemiol 99: 75–88; zit bei Sharrett AR (1977)

    PubMed  Google Scholar 

  • Poklis A (1975) The lead content of the aorta in male residents of Baltimore, Maryland. Bull Environ Contam Toxicol (4) 13: 417–419

    PubMed  Google Scholar 

  • Pribilla O, Schultek Th (1979) Blei-, Cadmium-, Chrom-, Mangan- und Zinkgehalt arteriosklerosefreier menschlicher Aorten. Z Rechtsmed 83: 273–281

    PubMed  Google Scholar 

  • Punsar S, Erametsa O, Karnoven MJ, Ryhanen A, Hilska P, Vornamo H (1973) zit bei Sharrett AR (1977)

  • Rachlin L (1972) Aortic zinc in patients with peripheral vascular disease. Angiology 23: 651–655

    PubMed  Google Scholar 

  • Ratschinkskij ID (1965) Nekotorije dannije o sodershanii mikroslementow zinka i medi w organach ljudei, umerschich ot aterosklerosa. In: Trudy IV Vsesojuznogo S'szda Patologoanatomov. Kisinev Medicina, Moskwa, S 71–72

    Google Scholar 

  • Rotter W (1978) Vorläufer und frühe Stadien der Atherosklerose und ihre Pathogenese. Med Welt (29) 27/28:1111–1114

    Google Scholar 

  • Schroeder HA (1960) Relations between hardness of water and death rates from certain chronic and degenerative diseases in the US. J Chronic Dis 12: 586–591

    PubMed  Google Scholar 

  • Sharrett AR (1977) Water hardness and cardiovascular disease. Elements in water and human tissues. Sci Total Environ 7: 217–226

    PubMed  Google Scholar 

  • Sharrett AR, Feinleib M (1975A) Water constituents and trace elements in relation to cardiovascular diseases. Prev Med 4: 20

    PubMed  Google Scholar 

  • Staub HW, Reussner G, Thiessen R (1969) Serum cholesterol reduction by chromium in hyper-cholesteremic rats. Science 166: 746–747

    PubMed  Google Scholar 

  • Thind GS (1972) Role of cadmium in human and experimental hypertension. J Air Pollut Control Assoc 22: 267–270

    PubMed  Google Scholar 

  • Volkow NF (1962) Sodershanie kobalta, marganza i zinka w krowi i wnutrennich organach ateroskleroso. Ter Arkh 34: 52–56

    Google Scholar 

  • Voors AW, Shuman MS, Gallagher PN (1975) Atherosclerosis and hypertension in relation to some trace elements in tissues. World Rev Nutr Diet 20: 299–326

    PubMed  Google Scholar 

  • Zechmeister A, Matonoha P (1977) Scanning electron microscope X-ray analysing of Ca, P, Fe, Si, K, Na, Mg, Zn, Co, and Mn in the wall of the young and the old (atherosclerotic) aorta. Folia Morphol (XXV) 4: 353–356

    Google Scholar 

  • Zlateva M, Antow G, Gwlwdowa W (1974) Ismenenija obmena belkow w stenke aorti pri wosdeistwii nekotorich tjashelich metallow. Gig Tr Prof Zabol (12) 0: 51–54

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Ausführliche Darstellung: Siehe Doktorarbeit H. Darmstäder, Lübeck 1979

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pribilla, O., Darmstädter, H. & Schultek, T. Blei-, Cadmium-, Chrom-, Mangan- und Zinkgehalt atherosklerotisch veränderter menschlicher Aorten. Z Rechtsmed 85, 127–137 (1980). https://doi.org/10.1007/BF02092202

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02092202

Key words

Schlüsselwörter

Navigation