Skip to main content
SpringerLink
Log in

Protective effect of tauroursodeoxycholate against acute gastric mucosal injury induced by hydrophobic bile salts

  • Letter To The Editor
  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Hofmann AF: Bile Acids.In The Liver: Biology and Pathobiology. IM Arias, WB Jakobi, H Popper, D Schachter, DA Shrafritz (eds), New York, Raven Press, 1986, pp. 553–572

    Google Scholar 

  2. James OFW: Ursodeoxycholic acid treatment of chronic cholestatic liver disease. J Hepatol 11:5–8, 1990

    Google Scholar 

  3. Stefaniwsky AB, Tint GS, Speck J, Shefer S, Salen G: Ursodeoxycholic acid treatment of bile reflux gastritis. Gastroenterology 89:1000–1004, 1985

    Google Scholar 

  4. Pazzi P, Scalia S, Stabellini G, Trevisani L, Alvisi V, Guarnieri M: Bile reflux gastritis in patients without prior gastric surgery: Therapeutic effects of ursodeoxycholic acid. Curr Ther Res 45:476–486, 1989

    Google Scholar 

  5. Armstrong D, Rytina ERC, Murphy GM, Dowling RH: Gastric mucosal toxicity of duodenal juice constituents in the rat. Acute studies usingex vivo rat gastric chamber model. Dig Dis Sci 39:327–339, 1994

    Google Scholar 

  6. Igimi H, Carey M: pH-solubility relations of chenodeoxycholic and ursodeoxycholic acids: Physical-chemical basis for dissimilar solution and membrane phenomena. J Lipid Res 21:72–90, 1980

    Google Scholar 

  7. Robert A, Nezamis JE, Lancaster C, Davis JP, Field SO, Hanchar AJ: Mild irritants prevent gastric mucosa necrosis through “adaptive cytoprotection” mediated by prostaglandins. Am J Physiol 245:G113-G121, 1983

    Google Scholar 

  8. Burden WR, Hodges RP, Hsu M, O'Leary JP: Alkaline reflux gastritis. Surg Clin North Am 71:33–44, 1991

    Google Scholar 

  9. Ota S, Tsukahara H, Terano A, Hata Y, Hiraishi H, Mutoh H, Sugimoto T: Protective effect of tauroursodeoxycholate against chenodeoxycholate-induced damage to cultured rabbit gastric cells. Dig Dis Sci 36:409–416, 1991

    Google Scholar 

  10. Guldutuna S, Zimmer G, Imhof M, Bhatti S, You T, Leuschner U: Molecular aspects of membrane stabilization by ursodeoxycholate. Gastroenterology 104:1736–1744, 1993

    Google Scholar 

  11. Hostein J, Bost R, Faure H, Lachet B, Fournet J: Valeur diagnostique de la pHmétrie gastrique au cours du reflux duodéno-gastrique. Gastroenterol Clin Biol 11:206–211, 1987

    Google Scholar 

  12. Batta AK, Salen G, Shefer S, Tint S, Dayal B: The effect of tauroursodeoxycholic acid and taurine supplementation on biliary bile acid composition. Hepatology 2:811–816, 1982

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Padua, Padua, Italy

    Maurizio Muraca MD, PhD, Eros Zanusso MD, Vito Cianci MD & Maria Teresa Vilei BSC

  2. Gastrointestinal Unit, Arcispedale S. Anna, Ferrara, Italy

    Paolo Pazzi MD, Mauro Dalla Libera MD & Susanna Gamberini MD

Authors
  1. Maurizio Muraca MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eros Zanusso MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vito Cianci MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Maria Teresa Vilei BSC
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Paolo Pazzi MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mauro Dalla Libera MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Susanna Gamberini MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This work was supported in part by CNR (D.P. 12795, Centro per lo studio dell'invecchiamento, Istituto di Medicina Interna, Università di Padova, Padua, Italy).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Muraca, M., Zanusso, E., Cianci, V. et al. Protective effect of tauroursodeoxycholate against acute gastric mucosal injury induced by hydrophobic bile salts. Digest Dis Sci 41, 1181–1182 (1996). https://doi.org/10.1007/BF02088235

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02088235

Keywords

Search

Navigation