Abstract
A rare case of a malignant Leydig-cell tumour of the testis in a 26-year-old patient, with radical orchiectomy from an inguinal incision is described. Although the results of AFP, HCG, biochemical, X-ray, lymphographic and scintigraphic examinations were negative, the first metastases into the lungs appeared one year after the operation. Combined cytostatic treatment, polychemotherapy and X-ray therapy proved ineffective. The patient died of multiple metastases 28 months after the surgical intervention.
Similar content being viewed by others
References
Collins, D. H., Cameron, K. M.: Interstitial-cell tumour.Br. J. Urol., 36, 62 (1964).
Colodny, A. H., Hopkins, T. B.: Testicular tumors in infants and children.Urol. Clin. North. Am., 4, 347 (1977).
Dixon, F. J., Moore, R. A.: Tumors of the male sex organs. Atlas of Tumor Pathology. Sect. VIII. Fa 31 b and 32. Armed Forces Institute of Pathology, Washington 1952.
Hopkins, G. B.: Interstitial cell tumor of testis.J. Urol., 103, 449 (1970).
Johnston, G.: Prepubertal gynecomastia in association with an interstitial-cell tumor of testis.Br. J. Urol., 39, 211 (1967).
Markland, G.: Special problems in managing patients with testicular cancer.Urol. Clin. North Am., 4, 427 (1977).
Mostofi, F. K., Price, E. B., Jr.: Tumors of the male genital system. Atlas of Tumor Pathology, Sect. 2. Fa VIII. Armed Forces Institute of Pathology, Washington 1973.
Mostofi, F. K., Sobia, L. H.: Histological typing of testis tumours. World Health Organization, Geneva 1977.
Ribbat, O., Engelking, R., Seiferth, J., Hübner, G., Schaefer, H. E.: Clinical and therapeutical aspects of Leydig-cell tumors.Z. Urol. Nephrol., 66, 593 (1973).
Silverberg, S. G., Thompson, J., Higashi, G., Baskin, A. M.: Malignant interstitial cell tumor of testis, case report and review.J. Urol., 96, 356 (1966).
Zvara, V., Horňák, M., Kossey, P., in cooperation with Heads of Urology Departments of the Slovak Socialist Republic (SSR). Testicular tumors — an analysis of clinical patients from the SSR, during the period 1965–1974.Rozhl. Chir., 55, 576 (1976).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Červenakov, I., Lepieš, P., Mardiak, J. et al. Malignant Leydig-cell tumour of testis. International Urology and Nephrology 16, 227–232 (1984). https://doi.org/10.1007/BF02082567
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02082567