Abstract
Although blue-green molds of the genusPenicillium are ubiquitous in the human environment, invasive penicilliosis is uncommon and primarily encountered among immunosuppressed patients. A patient with HIV infection who died of severe necrotizing esophagitis caused byPenicillium chrysogenum is reported and the relevant English language literature on human penicilliosis is reviewed. Although infectious esophagitis is commonly associated with AIDS,Penicillium esophagitis has not been described in such patients.
Similar content being viewed by others
References
Groopman JE: The acquired immunodeficiency syndrome. In: Wyngaarden JB, Smith LH (ed): Cecil textbook of medicine. Saunders, Philadelphia, 1988, p. 1799–1808.
Chamberland ME, Curran JW: Epidemiology and prevention of AIDS and HIV infection. In: Mandell GL, Douglas RG, Bennett JE (ed): Principles and practices of infectious diseases. Churchill Livingstone, New York, 1990, p. 1029–1046.
Rippon JW: Hyalohyphomycosis. In: Rippon JW (ed): Medical mycology. Saunders, Philadelphia, 1988, p. 728–730.
Jayanetra P, Nitiyanant P, Ajello L, Padhye AA, Lolekha S, Atichartakarn V, Vathesatogit P, Sathaphatayavongs B, Prajaktam R:Penicilliosis marneffei in Thailand: report of five human cases. American Journal of Tropical Medicine and Hygiene 1984, 33: 637–644.
Deng ZL, Ma Y, Ajello L: HumanPenicilliosis marneffei and its relation to the bamboo rat (Rhizomys pruinosus). Journal of Medicine and Veterinary Mycology 1986, 24: 383–389.
Deng ZL, Ribas JL, Gibson DW, Connor DH: Infections caused byPenicillium marneffei in China and Southeast Asia: review of eighteen published cases and report of four more Chinese cases. Review of Infectious Diseases 1988, 10: 640–652.
Cello JP: AIDS-associated gastrointestinal disease. In: Sande MA, Volberding PA (ed): The medical management of AIDS. Saunders, Philadelphia, 1990, p. 145–160.
Fenech FF, Mallia CP: Pleural effusion caused byPenicillium lilacinum. British Journal of Diseases of Chest 1972, 66: 284–290.
Schlueter DP: “Cheesewashers' disease”: a new occupational hazard? Annals of Internal Medicine 1973, 78: 606.
Smyth GDL: Fungal infection in otology. British Journal of Dermatology 1964, 76: 425–428.
Morriss FH, Spock A: Intracranial aneurysm secondary to mycotic orbital and sinus infection. American Journal of Diseases of Children 1970, 119: 357–362.
Eschete ML, King JW, West BC, Oberle A:Penicillium chrysogenum endophthalmitis: first reported case. Mycopathologia 1981, 74: 125–127.
Gilliam JS, Vest SA:Penicillium infection of the urinary tract. Journal of Urology 1951, 65: 484–489.
Huang SN, Harris LS: Acute disseminated penicillosis: report of a case and review of pertinent literature. American Journal of Clinical Pathology 1963, 39: 167–174.
Disalvo AF, Fickling AM, Ajello L: Infection caused byPenicillium marneffei: description of first natural infection in man. American Journal of Clinical Pathology 1973, 60: 259–263.
Peto TE, Bull R, Millard PR, Mackenzie DW, Campbell CK, Haines ME, Mitchell RG: Systemic mycosis due toPenicillium marneffei in a patient with antibody to human immunodeficiency virus. Journal of Infections 1988, 16: 285–290.
Piehl MR, Kaplan RL, Haber MH: Disseminated penicilliosis in a patient with acquired immunodeficiency syndrome. Archives of Pathology and Laboratory Medicine 1988, 112: 1262–1264.
Alvarez S: Systemic infection caused byPenicillium decumbens in a patient with acquired immunodeficiency syndrome. Journal of Infectious Diseases 1990, 162: 283.
Upshaw CB: Penicillium endocarditis of aortic valve prosthesis. Journal of Thoracic and Cardiovascular Surgeries 1974, 68: 428–431.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hoffman, M., Bash, E., Berger, S.A. et al. Fatal necrotizing esophagitis due toPenicillium chrysogenum in a patient with acquired immunodeficiency syndrome. Eur. J. Clin. Microbiol. Infect. Dis. 11, 1158–1160 (1992). https://doi.org/10.1007/BF01961135
Issue Date:
DOI: https://doi.org/10.1007/BF01961135