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Massive striatal dopamine release in acute cerebral ischemia in rats

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Summary

Extracellular dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and cerebral blood flow were simultaneously determined using in vivo brain dialysis and a hydrogen clearance method in the striatum of spontaneously hypertensive rats during ischemia and after recirculation. Massive striatal dopamine release was demonstrated in acutely induced ischemic brain.

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Authors and Affiliations

  1. The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Maidashi 3-1-1, Higashi-ku, 812, Fukuoka City, Japan

    H. Yao, S. Sadoshima, T. Ishitsuka, T. Nagao & M. Fujishima

  2. Center for Emotional and Behavioral Disorders, Hizen National Mental Hospital, Kanzaki, 842-01, Saga, Japan

    T. Tsutsumi & H. Uchimura

Authors
  1. H. Yao
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  2. S. Sadoshima
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  3. T. Ishitsuka
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  4. T. Nagao
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  5. M. Fujishima
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  6. T. Tsutsumi
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  7. H. Uchimura
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Yao, H., Sadoshima, S., Ishitsuka, T. et al. Massive striatal dopamine release in acute cerebral ischemia in rats. Experientia 44, 506–508 (1988). https://doi.org/10.1007/BF01958929

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  • DOI: https://doi.org/10.1007/BF01958929

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