Summary
Among 9 benzodiazepines, tested on the proliferation of synchronously dividing flagellate cells, only diazepam and medazepam can induce an accumulation of abnormal mitotic figures after 24 h of treatment. It seems that there is not a direct relation between the activity of benzodiazepines on the central nervous system and their ability to inhibit mitosis.
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Miernik, A., Santa-Maria, A. & Marano, F. The antimitotic activities of some benzodiazepines. Experientia 42, 956–958 (1986). https://doi.org/10.1007/BF01941778
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DOI: https://doi.org/10.1007/BF01941778