Riassunto
L'allofusicoccina e l'isofusicoccina, due isomeri della fusicoccina isolati dai brodi di coltura diFusicoccum amygdali Del., differiscono dalla fusicoccina solamente per la posizione del gruppo acetossilico sul residuo del glucosio; nella prima questo è sul C-2′ e nella seconda sul C-4′. Fusicoccina, allofusicoccina e isofusicocina, nonchè i loro 19-deacetilderivati ed i sei corrispondenti diidroderivati, si interconvertono a pH leggermente alcalino a temperatura ambiente.
References
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Similar results have been recently reported byBarrow et al.8.
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UV-spectra were recorded on ethanolic solutions with a Beckman DK-2 spectrophotometer: all compounds showed only final absorption. IR-spectra were recorded in KBr pellets with a Beckman IR-9 spectrophotometer. NMR-spectra were recorded on a Varian HA-100 apparatus (unless otherwise stated) with TMS as an internal reference. Optical rotations were measured with a Perkin Elmer 141 polarimeter on ethanolic solutions. Mass spectra were recorded on an A. E. I. MS-902 spectrometer. Melting points are uncorrected. All compounds gave satisfactory elementary analyses.
We are grateful to Dr.L. Paolillo for the 220 MHz spectra of fusicoccin and isofusicoccin.
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Like fusicoccin2,3, compound VIII gave also transacetylation ions atm/e 680 and 722.
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This work was supported in part by the Italian Research Council (CNR). The technical assistance of Drs.F. Maietta andM. Scotto Lavinia is gratefully acknowledged.
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Ballio, A., Casinovi, C.G., Framondino, M. et al. The structures of isofusicoccin and allofusicoccin. Experientia 28, 126–127 (1972). https://doi.org/10.1007/BF01935707
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DOI: https://doi.org/10.1007/BF01935707