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Comparison of human adult and fetal hemoglobin: Aminophenol-induced methemoglobin formation

  • Pharmacologica
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Summary

Human fetal hemoglobin was more susceptible to methemoglobin formation in the presence of aminophenols than was adult hemoglobin. This was due to the intrinsic properties of the proteins rather than the presence of methemoglobin reductases.

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Authors and Affiliations

  1. Department of Pharmacology, Stella and Charles Guttman Laboratories for Human Pharmacology and Pharmacogenetics, New York University School of Medicine, 10016, New York, N.Y., USA

    M. Wind & A. Stern

Authors
  1. M. Wind
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  2. A. Stern
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Additional information

This work was supported by a grant from the National Institute of General Medical Sciences GM-17184.

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Wind, M., Stern, A. Comparison of human adult and fetal hemoglobin: Aminophenol-induced methemoglobin formation. Experientia 33, 1500–1501 (1977). https://doi.org/10.1007/BF01918834

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  • DOI: https://doi.org/10.1007/BF01918834

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