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Hyperplasia of Brunner glands: The spectrum of its radiographic manifestations

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Abstract

Radiographic features of the duodenal mucosa were analyzed in a series of 26 patients in whom the diagnosis of Brunner gland hyperplasis (BGH) had been established by endoscopic biopsies. The observed mucosal patterns could be classified into five categories: (1) focal BGH causing a solitary submucosal adenoma or a cluster of sessile polyps in the otherwise smooth duodenal bulb surface (five cases); (2) diffuse BGH manifested by a myriad of small and uniform mucosal elevations (six cases); (3) multifocal BGH producing large and well-demarcated polygonal masses (six cases); (4) BGH with concomitant acute and/ or chronic duodenitis showing marked thickening and nodularity of duodenal folds (four cases); or (5) BGH with predominant erosive duodenitis, leading to ulcerations (five cases). These radiographic findings showed a good correlation with the endoscopic and histopathologic manifestations of BGH and the frequently coexistent duodenitis.

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References

  1. Franzin G, Musola R, Ghidini O, Manfrini C, Frattom A. Nodular hyperplasia of Brunner's glands.Gastrointest Endosc 1985; 31:374–378

    PubMed  Google Scholar 

  2. Scagliosi G. Beitrag zur Aetiologie des Duodenalgeschwures.Virchows Arch [A] 1913; 214:220–279

    Google Scholar 

  3. Golden R. Nonmalignant tumors of the duodenum. AJR 1928; 20:405–413

    Google Scholar 

  4. Dodd GD, Fishler JS, Park OK. Hyperplasia of Brunner's glands: report of two cases with review of the literature.Radiology 1953; 60:814–821

    PubMed  Google Scholar 

  5. Berman V, Goldberg MJ. Hyperplasia of Brunner's glands.Br J Radiol 1959; 32:241–243

    PubMed  Google Scholar 

  6. Weinberg PE, Levin B. Hyperplasia of Brunner's glands.Radiology 1965; 84:259–262

    PubMed  Google Scholar 

  7. Schulman A. The cobblestone appearance of the duodenal cap, duodenitis and hyperplasia of Brunner's glands.Br J Radiol 1970; 43:787–795

    PubMed  Google Scholar 

  8. Jones B, Bayless TM, Hamilton SR, Yardley JH. “Bubbly” duodenal bulb in celiac disease: radiologic-pathologic correlation.AJR 1984; 142:119–122

    PubMed  Google Scholar 

  9. Agha FP, Ghahremani GG, Tsang TK, Victor TA. Heterotopic gastric mucosa in the duodenum: radiographic findings.AJR 1988; 150:291–294

    PubMed  Google Scholar 

  10. Robertson HE. The pathology of Brunner's glands.Arch Pathol 1941; 31:112–130

    Google Scholar 

  11. Gelfand DW, Wheeler JD, Ott DJ, Wu WC, Kerr RM, Munitz HA, Chen YM. Duodenitis: endoscopic-radiologic correlation in 272 patients.Radiology 1985; 157:577–581

    PubMed  Google Scholar 

  12. Govoni AF. Benign lymphoid hyperplasia of the duodenal bulb.Gastrointest Radiol 1976; 121:267–269

    Google Scholar 

  13. Kaplan EL, Dyson WL, Fitts WT. The relationship of gastric hyperacidity to hyperplasia of Brunner's glands.Arch Surg 1969; 98:636–639

    PubMed  Google Scholar 

  14. Stokes JF, Turnberg LA, Hawksley JC. Hyperplasia of Brunner's glands.Gut 1954; 5:469–474

    Google Scholar 

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Merine, D., Jones, B., Ghahremani, G.G. et al. Hyperplasia of Brunner glands: The spectrum of its radiographic manifestations. Gastrointest Radiol 16, 104–108 (1991). https://doi.org/10.1007/BF01887320

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  • DOI: https://doi.org/10.1007/BF01887320

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