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Recovery of the electrocorticogram of canine brains after complete cerebral ischaemia at 37° and 32°C

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Summary

Complete cerebral ischemia was produced in totally isolated dog heads, perfused from a donor dog. The temperature of the isolated brain was kept constant before, during and after the complete ischaemia, at either 37° C or 32° C. At a brain temperature of 37°C electrocortical potentials were found to reappear spontaneously as long as complete ischaemia did not exceed 50 min. In canine brains kept at a temperature of 32° C no reappearance of spontaneous electrical activity occured if ischaemia exceeded 100 min.

Zusammenfassung

Komplette Gehirnischämien wurden an völlig vom Rumpf getrennten Hundeköpfen gesetzt, die von einem Spenderhund perfundiert wurden. Die Gehirntemperatur dieser Köpfe wurde vor, während und nach kompletter Ischämie konstant auf 37° C oder auf 32° C gehalten. Bei einer Gehirntemperatur von 37° C betrug die maximale Dauer einer kompletten Ischämie, nach der noch ein Electrocorticogramm wiederkehrte, 50 min. Bei einer Gehirntemperatur von 32° C betrug diese Zeit 100 min.

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Hirsch, H., Tesch, P. Recovery of the electrocorticogram of canine brains after complete cerebral ischaemia at 37° and 32°C. Neurosurg. Rev. 5, 49–54 (1982). https://doi.org/10.1007/BF01793632

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