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Antiandrogentherapie der pathologisch gesteigerten und abartigen Sexualität des Mannes

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Zusammenfassung

Mit 100 mg Cyproteronacetat (1.2α-Methylen-6-chlor-Δ4,6-pregnadien-17α-ol-3.20-dion-17α-acetat) pro Tag per os konnten innerhalb von 10–14 Tagen Libido und Potenz hypersexuell bzw. abartig sexuell erregter Männer unabhängig vom Lebensalter in bisher 17 behandelten Fällen ohne Therapieversager und ohne wesentliche Nebenwirkungen gehemmt werden.

Summary

With 100 mg Cyproteroneacetate (1.2α-methylene-6-chloro-Δ4,6-pregnadiene-17α-ole-3.20-dione-17α-acetate) orally applied per day libido and potency of men suffering from hyper- or abnormal sexuality were inhibited within 10 to 14 days independent from the age of the patients in 17 cases up to this time without any failure in therapy and without fundamental side effects.

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Literatur

  • Neumann, F.: Methods for evaluating antisexual hormones. Methods in drug evaluation. Proc. Internat. Symposion Milano, 20.–23. Sept. 1965. Amsterdam: North Holland Publishing Comp. 1966.

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  • Neumann, F., andW. Elger: Physiological and psychical intersexuality of male rats by early treatment with an anti-androgenic agent (1.2.α-Methylene-6-chloro-Δ6-hydroxyprogesterone-acetate). Acta endocr. (Kbh.), Suppl.100, 174 (1965).

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  • Neumann, F., W. Elger, R. von Berswordt-Wallrabe u.M. Kramer: Beeinflussung der Regelmechanismen des Hypophysenzwischenhirnsystems von Ratten durch einen Testosteron-Antagonisten, Cyproteron (1.2α-Methylen-6-chlor-Δ4,6-pregnadien-17α-ol-3.20-dion). Naunyn-Schmiedebergs Arch. Pharmak. exp. Path.255, 221–235 (1966).

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Authors and Affiliations

  1. Psychoendokrinologische Abteilung der Pfälzischen Nervenklinik Landeck über Bergzabern, Germany

    Ursula Laschet & Leonhard Laschet

Authors
  1. Ursula Laschet
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  2. Leonhard Laschet
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Laschet, U., Laschet, L. Antiandrogentherapie der pathologisch gesteigerten und abartigen Sexualität des Mannes. Klin Wochenschr 45, 324–325 (1967). https://doi.org/10.1007/BF01747114

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  • DOI: https://doi.org/10.1007/BF01747114

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