Skip to main content

Advertisement

SpringerLink
Log in

Noninvasive recording of His bundle activity with an analog delay device in normal subjects and patients with atrioventricular block

  • Originals
  • Published:
Heart and Vessels Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

A simplified and clinically applicable method has been developed for real-time noninvasive recording of the electrical activity of the His bundle in the human heart. A surface electrocardiogram (ECG) was obtained from bipolar precordial leads. The electrical signal within the P-QRS segment of the ECG was amplified with a high gain amplifier and delayed with an analog delay device for QRS-triggered signal averaging. The analog delay device consisted of a bucket brigade device (BBD) with an electrical integrated circuit (IC). After filtering with a band width of 50–300Hz, the delayed signal was processed by a microcomputer system and the signal-to-noise ratio of the signal was improved by the signal averaging technique.

Surface His bundle electrocardiograms (SHE) were measured in normal subjects without conduction disorders and in patients with atrio-ventricular (A–V) block. In the same patients, each SHE was nonsimultaneously compared with an invasive His bundle electrogram (HBE) obtained by the intracardiac catheter technique. The results of this comparison confirmed that the noninvasive method of SHE recording has broad clinical applicability and high utility for the screening of patients with latent A–V block before intracardiac catheterization is performed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Alanis J, Gonzalez JH, Lopez E (1958) The electrical activity of the bundle of His. J Physiol 142:127–140

    PubMed  Google Scholar 

  2. Damato AN, Lau SH, Helfant RH, Stein E, Patton RD, Schelag BJ, Berkowitz WD (1969) A study of heart block in man using His bundle recordings. Circulation 39:297–305

    PubMed  Google Scholar 

  3. Damato AN, Lau SH, Berkowits WD, Rosen KM, Lisi KR (1969) Recording of specialized conducting fibers (A–V nodal, His bundle, and right bundle branch) in man using an electrode catheter technic. Circulation 39: 435–447

    PubMed  Google Scholar 

  4. Scherlag BJ, Lau SH, Helfant RH, Berkowitz WD, Stein E, Damato AN (1969) Catheter technique for recording His bundle activity in man. Circulation 39:13–18

    PubMed  Google Scholar 

  5. Scherlag BJ, Samet P, Helfant RH (1972) His bundle electrogram. A critical appraisal of its uses and limitations. Circulation 46:601–613

    PubMed  Google Scholar 

  6. Berbari EJ, Lazzara R, Samet P, Scherlag BJ (1973) Noninvasive technique for detection of electrical activity during the P–R segment. Circulation 48:1005–1011

    PubMed  Google Scholar 

  7. Flowers NC, Hand RC, Orander PC, Miller CB, Walden MO, Horan LG (1974) Surface recording of electrical activity from the region of the bundle of His. Am J Cardiol 33:384–389

    PubMed  Google Scholar 

  8. Berbari EJ, Lazzara R, El-Sherif N, Scherlag BJ (1975) Extracardiac recording of His-Purkinje activity during conduction disorders and junctional rhythms. Circulation 51:802–810

    PubMed  Google Scholar 

  9. Hisimoto Y, Sawayama T (1975) Non-invasive recording of His bundle potential in man. Simplified method. Br Heart J 37:635–639

    PubMed  Google Scholar 

  10. Furness A, Sharratt GP, Garson P (1975) The feasibility of detecting His-bundle activity from the body surface. Cardiovasc Res 9:390–396

    PubMed  Google Scholar 

  11. VandenAkker TJ, Ros HH, Goovaerts HG, Schneider H (1976) Real-time method for noninvasive recording of His bundle activity of the electrocardiogram. Comput Biomed Res 9:559–569

    PubMed  Google Scholar 

  12. Berbari EJ, Scherlag BJ, El-Sherif N, Befeler B, Aranda JM, Lazzara R (1976) The His-Purkinje electrocardiogram in man. An initial assessment of its uses and limitations. Circulation 54:219–224

    PubMed  Google Scholar 

  13. Wajszczuk WJ, Stopczyk MJ, Moskowitz MS, Zochowski RJ, Bauld T, Dabos PL, Rubenfire M (1978) Noninvasive recording of His-Purkinje activity in man by QRS-triggered signal averaging. Circulation 58:95–102

    PubMed  Google Scholar 

  14. Takeda H, Kitamura K, Takanashi T, Tokuoka T, Hamamoto H, Katoh T, Niki I, Hishimoto Y (1979) Noninvasive recording of His-Purkinje activity in patients with complete atrioventricular block. Clinical application of an “automated discrimination circuit.” Circulation 60:421–426

    PubMed  Google Scholar 

  15. Mehra R, Kelen GJ, Zephiran D, Fried P, Gomes JA, El Sherif N (1982) Noninvasive His bundle electrogram: Value of three vector lead recordings. Am J Cardiol 49:344–348

    PubMed  Google Scholar 

  16. Nathan AW, Bexton RS, Levy AM, Parmar N, Camm AJ (1984) Noninvasive recording of the His bundle electrogram in neonates. Pediatr Cardiol 5:7–12

    PubMed  Google Scholar 

  17. Biour M, Weissenburger J, Poirier JM, Le Heuzey JY, Gay F, Cazaux P, Cheymol G (1989) Recording of the His bundle potential at the surface of the thorax in healthy volunteers. Application to the study of pnopranolol. Therapie 44:9–11

    PubMed  Google Scholar 

  18. de Feyter HJ, Ros HH, Majid PA, van Eenige MJ, Karreman J, Ross JP (1981) Clinical evaluation of Hisbundle electrogram recorded from the body surface. Clin Cardiol 4:80–86

    PubMed  Google Scholar 

  19. Rozanski JJ, Gastellanos A (1980) Clinical evaluation of an improved high resolution ECG cart for recording the His bundle electrogram non-invasively. PACE 3:479–484

    PubMed  Google Scholar 

  20. Flowers NC, Shvartsman V, Horan LG, Palakurthy P, Sohi G, Sridharan MR (1983) Analysis of PR subintervals in normal subjects and early studies in patients with abnormalities of the conduction system using surface His bundle recordings. JACC 2:939–946

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology, School of Allied Medical Sciences, Shinshu University, 3-1-1 Asahi, 390, Matsumoto, Japan

    Yoshihisa Ushiyama

  2. Nagano National College of Technology, 716 Tokuma, 381, Nagano, Japan

    Hideo Okajima

  3. Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, 390, Matsumoto, Japan

    Yoshiyuki Sasaki

  4. Department of Vascular Physiology, National Cardiovascular Center Research Institute, 5-7-1 Fujishiro-dai, 565, Suita, Japan

    Masamitsu Hasegawa

Authors
  1. Yoshihisa Ushiyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hideo Okajima
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yoshiyuki Sasaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Masamitsu Hasegawa
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ushiyama, Y., Okajima, H., Sasaki, Y. et al. Noninvasive recording of His bundle activity with an analog delay device in normal subjects and patients with atrioventricular block. Heart Vessels 10, 241–248 (1995). https://doi.org/10.1007/BF01744903

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01744903

Key words

Search

Navigation