Abstract
Pulsed-field gel electrophoresis was used to analyze the DNA of 67Neisseria meningitidis A strains from five African outbreaks occurring between 1988 and 1996. EndonucleaseBglII was used to cut chromosomal DNA, generating 19 analyzable fragments. This technique allowed comparison of clonal relationships between outbreak strains and revealed that the same pulsotype was responsible for the outbreaks. This pulsotype is closely related to strain B54, subgroup III reference strain, Finland, 1975, showing only two fragment differences.
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Nicolas, P., Parzy, D. & Martet, G. Pulsed-field gel electrophoresis analysis of clonal relationships amongNeisseria meningitidis A strains from different outbreaks. Eur. J. Clin. Microbiol. Infect. Dis. 16, 541–544 (1997). https://doi.org/10.1007/BF01708241
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DOI: https://doi.org/10.1007/BF01708241