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Low-dose aclarubicin in blastic transformation of essential thrombocythemia

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Summary

We attempted treatment with low-dose aclarubicin (ACR), a new anthracycline, in a 66-year-old man with blastic transformation of essential thrombocythemia (ET). Two courses of ACR (20 mg/day x 7 days) were given intravenously. He showed a good response to this therapy without severe side effects. He has since maintained a state of prolonged remission. These observations indicate that low-dose ACR may be beneficial for management of the blastic transformation of ET.

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Authors and Affiliations

  1. Department of Internal Medicine, Munakata Medical Association Hospital, 1201-1 Taguma, Munakata, 811-34, Fukuoka, Japan

    Y. Asano, Y. Naritomi, H. Kimura, Y. Maeda & T. Kusaba

  2. Shinkokura Hospital, Kitakyushu, 803, Fukuoka, Japan

    S. Yoshizawa & G. Shiraishi

Authors
  1. Y. Asano
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  2. Y. Naritomi
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  3. H. Kimura
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  4. Y. Maeda
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  5. T. Kusaba
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  6. S. Yoshizawa
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  7. G. Shiraishi
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Asano, Y., Naritomi, Y., Kimura, H. et al. Low-dose aclarubicin in blastic transformation of essential thrombocythemia. Ann Hematol 62, 194–195 (1991). https://doi.org/10.1007/BF01703149

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  • DOI: https://doi.org/10.1007/BF01703149

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