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Rheumatoid arthritis: Review of searches for an infectious cause. Part II

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Literature

  1. Hirschhorn, R. N. The blind men and the rheumatoid elephant. N. Engl. J. Med. 292 (1975) 554–555.

    Google Scholar 

  2. Schlosstein, L., Terasaki, P., Bluestone, R., Pearson, C. M. High association of an HL-A antigen, W-27, with ankylosing spondylitis. N. Engl. J. Med. 288 (1973) 704–706.

    Google Scholar 

  3. Brewerton, D. A., Hart, F. D., Nicholls, A., Caffrey, M., James, D. C. O., Sturrock, R. D. Ankylosing spondylitis and HL-A 27. Lancet I (1973) 904–907.

    Google Scholar 

  4. Morris, P. J., Metzger, A. L., Bluestone, R., Terasaki, P. I. HL-A 27 — a clue to the diagnosis and pathogenesis of Reiters' syndrome. N. Engl. J. Med. 290 (1974) 554–556.

    Google Scholar 

  5. Stastny, P. Typing by compatibility in mixed lymphocyte culture using LD-homozygous typing cells. Transplant Proc. 9 Suppl. 1 (1977) 73–75.

    Google Scholar 

  6. Zabriskie, J. B. Rheumatic fever: a streptococcal-induced autoimmune disease. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Blackwell, Oxford, 1976, p. 97–111.

    Google Scholar 

  7. Lambert, P. A., Nydegger, V. E., Perrin, L. H., McCormic, J., Fehr, K., Miescher, P. A. Immune complexes and complement activation in rheumatoid arthritis. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Blackwell, Oxford, 1976, p. 409–411.

    Google Scholar 

  8. Zvaifler, N. J. Breakdown products of C3 in human synovial fluids. J. Clin. Invest. 48 (1969) 1532–1542.

    Google Scholar 

  9. Ruddy, S. Activation of the complement and properdin systems in rheumatoid arthritis. Ann. N.Y. Acad. Sci. 256 (1975) 96–104.

    Google Scholar 

  10. Ruddy, S., Fearon, D. T., Austen, K. F. Depressed synovial fluid levels of properdin and properdin factor B in rheumatoid arthritis. Arthritis Rheum. 18 (1975) 238–295.

    Google Scholar 

  11. Holborow, E. J. Antiglobulins and antinuclear antibodies viewed as responses to infection. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Black-well, Oxford, 1976, pp. 431–433.

    Google Scholar 

  12. Natvig, J. B., Gaarder, P. I., Turner, M. W. IgG antigens of the C γ 2 and C γ 3 homology regions interacting with rheumatoid factors. Clin. Exp. Immunol. 12 (1972) 177–184.

    Google Scholar 

  13. Milgram, F., Dubiski, S., Wozniczko, G. Human sera with ‘anti-antibody.’ Vox Sang. 1 (1956) 172–183.

    Google Scholar 

  14. Natvig, J. B. Reaction of human anti-antibodies with incomplete anti-D and its subunits. Acta Path. Microbiol. Scand. 66 (1966) 369–382.

    Google Scholar 

  15. Mellbye, O. J., Natvig, J. B. Evidence for immune complexes containing antibody to the pepsin site of IgG in rheumatoid synovial fluids. Clin. Exp. Immunol. 8 (1971) 889–899.

    Google Scholar 

  16. Natvig, J. B., Frøland, S. S., Wisløff, F., Munthe, E. Anti-Ig activities in rheumatoid arthritis related to different lymphocyte subpopulations. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Blackwell, Oxford, 1976, pp. 449–456.

    Google Scholar 

  17. Kunkel, H. G., Tan, E. M. Autoantibodies and disease. Adv. Immunol. 4 (1964) 351–395.

    Google Scholar 

  18. Winchester, R. J., Agnello, V., Kunkel, H. G. Gamma globulin complexes in synovial fluids of patients with rheumatoid arthritis. Clin. Exp. Immunol. 6 (1970) 689–706.

    Google Scholar 

  19. Vaughan, J. H., Jacox, R. F., Abraham, G., Clark, R. Relation of rheumatoid factor to intracellular inclusions. Ann. N. Y. Acad. Sci. 168 (1969) 111–119.

    Google Scholar 

  20. Munthe, E., Natvig, J. B. Characterization of IgG complexes from rheumatoid tissue. Clin. Exp. Immunol. 8 (1979) 249–262.

    Google Scholar 

  21. Munthe, E. Complexes of IgG and IgG rheumatoid factor in synovial tissues of juvenile rheumatoid arthritis. Scand. J. Rheumatol. 1 (1972) 153–160.

    Google Scholar 

  22. Geiler, G. Proliferative and exudative features of the rheumatoid synovium. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Blackwell, Oxford, 1976, pp. 413–416.

    Google Scholar 

  23. Bacon, P. A., Weisbart, R. H., Cracchiolo, A., Bluestone, R., Goldberg, L. S. Cellular immunity to synovial extracts and to IgG in rheumatoid arthritis. In:Dumonde, D. C. (ed.): Infection and immunology in the rheumatic diseases. Black-well, Oxford, 1976, p. 479.

    Google Scholar 

  24. Rothenberger, W., Thiele, H. G. Leucocyte migration inhibition in rheumatoid arthritis. Lancet II (1971) 372.

    Google Scholar 

  25. Brostoff, J., Freedman, A., Roitt, I. M. Leucocyte migration inhibition to Mycoplasma fermentans in patients with rheumatoid arthritis. Int. Arch. Allergy 45 (1973) 690–696.

    Google Scholar 

  26. Munthe, E., Høyeraal, H. M., Frøland, S. S., Mellbye, O. J., Kass, E., Natvig, J. B. Evidence denoting complement activation by the alternative pathway in the arthritis of hypogammaglobulinemic patients. Rheumatism 6 (1975) 43–51.

    Google Scholar 

  27. Silverman, H. A., Johnson, J. S., Vaughan, J. H., McGlamory, J. C. Altered lymphocyte reactivity in rheumatoid arthritis. Arthritis Rheum. 19 (1976) 509–515.

    Google Scholar 

  28. Rawson, A. J., Huang, T. C. Lymphocytes in rheumatoid arthritis II. Quantitative binding of phytomitogens. Clin. Exp. Immunol. 16 (1974) 47–52.

    Google Scholar 

  29. Isturiz, M. A., De Bracco, M. M., Pizzi, A. M., Manni, J. A. Antibody-dependent cell-mediated cytotoxicity in rheumatoid arthritis: Effect of rheumatoid serum fractions on normal lymphocytes. Arthritis Rheum. 19 (1976) 725–730.

    Google Scholar 

  30. Steward, M. W. The role of low-affinity antibody in immune complex disease. In:Dumonde, D. C. (ed.): Infection and immunity in the rheumatic diseases. Blackwell, Oxford, 1976, pp. 439–444.

    Google Scholar 

  31. Zabriskie, J. B. Heart-reactive antibodies: do they cause rheumatic fever and the postpericardiotomy syndrome? Med. Times 105 (1977) 11 d-19 d.

    Google Scholar 

  32. Glynn, L. E. Infection and autoimmunity. In:Dumonde, D. C. (ed.): Infection and Immunology in the rheumatic diseases. Blackwell, Oxford, 1976, pp. 75–78.

    Google Scholar 

  33. Warren, S. L., Marmor, L., Liebes, D. M., Hollins, R. An active agent from human rheumatoid arthritis which is transmissible in mice: preliminary report. Arch. Int. Med. 124 (1971) 629–634.

    Google Scholar 

  34. Warren, S. L., Marmor, L., Boak, R., Liebes, D. M. Transmission of an active agent from rheumatoid arthritis synovial tissue to chicks. Arch. Int. Med. 128 (1971) 619–622.

    Google Scholar 

  35. Warren, S. L., Marmor, L., Liebes, D. M., Rosenblatt, H. M. An active agent from rheumatoid arthritis synovial tissue: Transmission by injection or ingestion in mice and rats. Arch. Int. Med. 130 (1972) 899–903.

    Google Scholar 

  36. Cole, B. C., Ward, J. R., Smith, C. B. Studies on the infectious etiology of rheumatoid arthritis. Arthritis Rheum. 16 (1973) 191–198.

    Google Scholar 

  37. Kruit, W. F., Feltkamp, T. E. W., De Blécourt, J. J., Nienhuis, R. L. F. Transmissibility of rheumatoid arthritis from men to mice. Arch. Int. Med. 131 (1973) 304.

    Google Scholar 

  38. Gottlieb, N. L., Ditchek, N., Poiley, J., Kiem, I. M. Pets and rheumatoid arthritis: an epidemiologic survey. Arthritis Rheum. 17 (1974) 229–234.

    Google Scholar 

  39. Bacon, P. A., Bluestone, R., Goldberg, L. S., Webb, F. W., Pearson, C. M., Cooke, M., Stevens, J. G. Experimental herpes viral arthritis: factors in chronicity. Ann. Rheum. Dis. 33 (1974) 413–421.

    Google Scholar 

  40. Webb, F. W., Bluestone, R., Goldberg, L. S., Douglas, S. D., Pearson, C. M. Experimental viral arthritis induced with herpes simplex. Arthritis Rheum. 16 (1973) 241–246.

    Google Scholar 

  41. London, W. T., Fuccillo, D. A., Anderson, B., Sever, J. L. Concentration of rubella virus antigen in chondrocytes of congenitally infected rabbits. Nature 226 (1970) 172–173.

    Google Scholar 

  42. Grazyel, A. I., Janis, R., Haberman, E. A chronic arthritis produced by the injection of rubella virus into the knee joints of rabbits. Arthritis Rheum. (Abst.) 14 (1971) 164.

    Google Scholar 

  43. Martenis, T. W., Bland, J. H., Philips, C. A. Rheumatoid arthritis after rubella. Arthritis Rheum. 11 (1968) 683–685.

    Google Scholar 

  44. Chiba, Y., Sadeghi, E., Ogra, P. L. Abnormalities of cellular immune response in arthritis induced by rubella vaccination. J. Immunol. 117 (1976) 1684–1687.

    Google Scholar 

  45. Linneman, C. C., Jr., Levinson, J. E., Buncher, C. R., Schiff, G. M. Rubella antibody levels in juvenile rheumatoid arthritis. Ann. Rheum. Dis. 34 (1975) 354–358.

    Google Scholar 

  46. Cassidy, J. T., Shillis, J. L., Brandon, F. B., Sullivan, D. B., Bracket, R. G. Viral antibody titers to rubella and rubeola in juvenile rheumatoid arthritis. Pediatrics 54 (1974) 239–244.

    Google Scholar 

  47. Phillips, P. E., Lim, W. N., Parkman, P. D., Hirshaut, Y. Virus antibody and IgG levels in juvenile rheumatoid arthritis. Arthritis Rheum. 16 (1973) 126.

    Google Scholar 

  48. Ogra, P. L., Chiba, Y., Ogra, S. S., Dzierba, J. L., Herd, J. K. Rubella-virus infection in juvenile rheumatoid arthritis. Lancet I (1975) 1157–1161.

    Google Scholar 

  49. Hart, H., Marmion, B. P. Rubella virus and rheumatoid arthritis. Ann. Rheum. Dis. 36 (1977) 3–12.

    Google Scholar 

  50. Kalliomäki, J. L., Halonen, P., Salmi, A. Virus antibodies in serum and synovial fluid of patients with rheumatoid arthritis and other connective tissue diseases. Ann. Rheum. Dis. 34 (1975) 43–48.

    Google Scholar 

  51. Phillips, P. E., Waxman, J., Hirshaut, Y., Kaplan, M. H. Virus antibody levels and delayed hypersensitivity in rheumatoid arthritis. Ann. Rheum. Dis. 35 (1976) 152–154.

    Google Scholar 

  52. Wilkes, R. M., Simsarian, J. P., Hopps, H. E., Roth, H., Decker, J. L., Aptekar, R. G., Meyer, H. M., Jr. Virologic studies on rheumatoid arthritis. Arthritis Rheum. 16 (1973) 446–454.

    Google Scholar 

  53. Phillips, P. E. Virologic studies in rheumatoid arthritis. Rheumatology 6 (1975) 353–360.

    Google Scholar 

  54. Burrell, C. J., Dickson, J. D., Gerber, H., McCormick, J. N., Marmion, B. P. Rheumatoid arthritis, rheumatoid factor, and tests for Australia or hepatitis-associated antigen. Brit. Med. J. 2 (1972) 23–24.

    Google Scholar 

  55. Middleton, P. J., Highton, T. C. Failure to show mycoplasmas and cytopathogenic virus in rheumatoid arthritis. Ann. Rheum. Dis. 34 (1975) 369–372.

    Google Scholar 

  56. Person, D. A., Sharp, J. T., Rawls, W. E. A search for viruses and mycoplasmas in connective tissue diseases. Arthritis Rheum. 16 (1973) 677–687.

    Google Scholar 

  57. Norval, M., Marmion, B. P. Attempts to identify viruses in rheumatoid synovial cells. Ann. Rheum. Dis. 35 (1976) 106–113.

    Google Scholar 

  58. Schumacher, H. R. Synovial membrane and fluid morphologic alterations in early rheumatoid arthritis: microvascular injury and virus-like particles. Ann. N.Y. Acad. Sci. 256 (1975) 39–64.

    Google Scholar 

  59. Helder, A. W., Feltkamp-Vroom, T. M., Nienhuis, R. L. F. Electron and light microscopial observations and serological findings in rheumatoid arthritis. Ann. Rheum. Dis. 32 (1973) 515–523.

    Google Scholar 

  60. Neumark, T., Hollos, I., Farkas, K. Virus-like particles in rheumatoid synovium. Scand. J. Rheumatol. 2 (1973) 21–28.

    Google Scholar 

  61. Schumacher, H. R. Tubular paramyxovirus-like structures in synovial vascular endothelium. Ann. Rheum. Dis. 29 (1970) 445–447.

    Google Scholar 

  62. Schumacher, H. R., Kitridou, R. C. Synovitis of recent onset: a clinicopathologic study during the first month of disease. Arthritis Rheum. 15 (1972) 465–485.

    Google Scholar 

  63. Györkey, E., Sinkovics, J. G., Min, K. W., Györkey, P. A morphologic study on the occurrence and distribution of structures resembling viral nucleocapsids in collagen diseases. Am. J. Med. 53 (1972) 148–158.

    Google Scholar 

  64. Molnar, Z., Metzger, A. L., McCarty, D. J. Tubular structures in endothelium in palindromic rheumatism. Arthritis Rheum. 15 (1972) 553–556.

    Google Scholar 

  65. Decker, J. L., Barden, J. A. Mycoplasma hyorhinis arthritis of swine: A model for rheumatoid arthritis? Rheumatology 6 (1975) 338–345.

    Google Scholar 

  66. Adler, H. E. Avian mycoplasmal diseases. In:Sharp, J. T. (ed.): The role of mycoplasmas and L forms of bacteria in disease. C. C. Thomas, Springfield, Illinois, 1970, p. 240.

    Google Scholar 

  67. Cole, B. C., Golightly-Rowland, L., Ward, J. R. Arthritis of mice induced by Mycoplasma arthritidis: Humoral antibody and lymphocyte response of CBA mice. Ann. Rheum. Dis. 35 (1976) 14–22.

    Google Scholar 

  68. Harwick, H. J., Kalmanson, G. M., Fox, M. A., Guze, L. B. Arthritis in mice due to infection with Mycoplasma pulmonis. I. Clinical and Microbiologic features. J. Infect. Dis. 128 (1973) 553–540.

    Google Scholar 

  69. Harwick, H. J., Mahoney, A. D., Kalmanson, G. M., Guze, L. B. Arthritis in mice to infection with Mycoplasma pulmonis. II. Serological and histological features. J. Infect. Dis. 133 (1976) 103–112.

    Google Scholar 

  70. Ward, J. R., Cole, B. C. Other murine mycoplasmas. In:Sharp, J. T. (ed.): The role of mycoplasmas and L forms of bacteria in disease. C. C. Thomas, Springfield, 1970.

    Google Scholar 

  71. Barile, M. F., Del Giudice, R. A., Carski, T. R., Gibbs, C. J., Morris, J. A. Isolation and characterization of Mycoplasma arginini: spec. nov. Proc. Soc. Exper. Biol. Med. 129 (1968) 489–494.

    Google Scholar 

  72. Cottew, G. S. Diseases of sheep and goats caused by mycoplasmas. In:Sharp, J. T. (ed.): The role of mycoplasmas and L-forms of bacteria in disease. C. C. Thomas, Springfield, Illinois, 1970, pp. 198–211.

    Google Scholar 

  73. Piercy, D. W., Bingley, J. B. Fibrinous synovitis in calves inoculated with killed Mycoplasma mycoides: Elevated plasma fibrinogen concentration and increased permeability of the synovium. J. Comp. Pathol. 82 (1972) 279–290.

    Google Scholar 

  74. Freundt, E. A. Present status of the medical importance of mycoplasma. Path. Microbiol. 40 (1974) 155–187.

    Google Scholar 

  75. Brown, T. McP., Clark, H. W., Bailey, J. S., Bray, C. W. A mechanistic approach to treatment of rheumatoid type arthritis naturally occuring in a gorilla. Trans. Am. Clin. Chim. Assoc. 82 (1970) 227–247.

    Google Scholar 

  76. Morton, H. E. Mycoplasmas from man with undetermined specific relationships to their human host. In:Sharp, J. T. (ed.): The role of mycoplasmas and L forms of bacteria in disease. C. D. Thomas, Springfield, 1970, pp. 147–171.

    Google Scholar 

  77. Stewart, S. M., Duthie, J. J. R., MacKay, J. M. K., Marmion, B. P., Alexander, W. R. M. Mycoplasmas and rheumatoid arthritis. Ann. Rheum. Dis. 33 (1974) 346–352.

    Google Scholar 

  78. Jansson, E., Vainio, V., Snellman, O., Tuuri, S. Search for mycoplasma in rheumatoid arthritis. Ann. Rheum. Dis. 30 (1971) 413–418.

    Google Scholar 

  79. Williams, M. H., Brostoff, J., Roitt, I. M. Possible role of Mycoplasma fermentans in pathogenesis of rheumatoid arthritis. Lancet II (1970) 277–280.

    Google Scholar 

  80. Mardh, P. A., Nilsson, F. J., Bjelle, A. Mycoplasmas and bacteria in synovial fluid from patients with arthritis. Ann. Rheum. Dis. 32 (1973) 319–325.

    Google Scholar 

  81. Brown, T. McP., Clark, H. W., Bailey, J. S.: The isolation of mycoplasma from pleural fluid in rheumatoid arthritis. 13th Internat. Congress Rheumatology, Kyoto, 1973.

  82. Arai, M. Mycoplasma in synovial fluid from the patients with rheumatoid arthritis. Tohoku J. Exp. Med. 115 (1975) 47–52.

    Google Scholar 

  83. Markham, J. G., Myers, D. B.: Preliminary observations on an isolate from synovial fluid of patients with rheumatoid arthritis. Ann. Rheum. Dis. (1976) 1–7.

  84. Webster, A. D., Loewi, G., Dourmashkin, R. D., Golding, D. N., Ward, D. J., Asherson, G. L. Polyarthritis in adults with hypogammaglobulinemia and its rapid response to immunoglobulin treatment. Br. Med. J. I (1976) 1314–1316.

    Google Scholar 

  85. Ford, D. K., Wort, B. Mycoplasmas and rheumatoid arthritis. Arthritis Rheum. 15 (1972) 650.

    Google Scholar 

  86. Person, D. A., Whitworth, M. E., Sharp, J. T. Mycoplasmas and rheumatoid arthritis. Arthritis Rheum. 15 (1972) 649–650.

    Google Scholar 

  87. Cole, B. C., Ward, J. R., Smith, C. B. Studies on the infectious etiology of rheumatoid arthritis. Arthritis Rheum. 16 (1973) 191–198.

    Google Scholar 

  88. Windsor, G. D., Nicholls, A., Maini, R. N., Edward, D. G. ff., Lemcke, R. M., Dumonde, D. C. Search for mycoplasma in synovial fluids from patients with rheumatoid arthritis. Ann. Rheum. Dis. 33 (1974) 70–74.

    Google Scholar 

  89. Person, D. A., Sharp, J. T., Rawls, W. E. A search for viruses and mycoplasmas in connective tissue diseases. Arthritis Rheum. 16 (1973) 677–687.

    Google Scholar 

  90. Kaklamis, E., Thomas, L., Stavropoulos, K., Borman, I., Boshwitz, C. Mycoplasmacidal action of normal tissue extracts. Nature 221 (1969) 860–862.

    Google Scholar 

  91. Williams, M. H., Bruchman, F. E. Immunological reactivity to Mycoplasma fermentans in patients with rheumatoid arthritis: Preliminary communication. Ann. Rheum. Dis. 30 (1971) 271–273.

    Google Scholar 

  92. Jansson, E., Mäkisara, P., Tuuri, S. Mycoplasma antibodies in rheumatoid arthritis. Scand. J. Rheumatol. 4 (1975) 165–168.

    Google Scholar 

  93. Maini, R. N., Lemcke, R. M., Windsor, G. D., Rolfe, L. M., Magrath, I. T., Dumonde, D. C. The significance of leucocyte migration inhibition of M. fermentans. Rheumatology 6 (1975) 118–130.

    Google Scholar 

  94. Windsor, G. D., Nicholls, A., Maini, R. N., Edward, D. G. ff., Lemcke, R. M., Dumonde, D. C. Search for mycoplasma in synovial fluids from patients with rheumatoid arthritis. Ann. Rheum. Dis. 33 (1974) 70–74.

    Google Scholar 

  95. Brostoff, J., Roitt, I. M. Cellular reactions to mycoplasma and aggregated IgG in patients with rheumatoid arthritis. Rheumatology 6 (1975) 106–117.

    Google Scholar 

  96. Cole, B. C., Taylor, M. B., Ward, J. R. Studies on the infectious etiology of human rheumatoid arthritis. II. Search for humoral and cellbound antibodies against mycoplasmal antigens. Arthritis Rheum. 18 (1975) 435–441.

    Google Scholar 

  97. Chandler, R. W., Robinson, H., Masi, A. T. Serological investigations for evidence of an infectious etiology of rheumatoid arthritis. Ann. Rheum. Dis. 30 (1971) 274–278.

    Google Scholar 

  98. Stalheim, O. H. V.: Failure of antibiotic therapy in calves with mycoplasmal arthritis and pneumonia. J. Am. Vet. Med. Assoc. (1976) 1096–1097.

  99. Mansson, I., Norberg, R., Olhagen, B., Björklund, N. E. Arthritis in pigs induced by dietary factors, microbiologic, clinical and histologic studies. Clin. Exp. Immunol. 9 (1971) 677–693.

    Google Scholar 

  100. Olhagen, B. On the aetiopathogenesis of rheumatoid arthritis. Ann. Clin. Res. 7 (1975) 119–128.

    Google Scholar 

  101. Olhagen, B., Mansson, I. I. Intestinal Clostridium perfringes in rheumatoid arthritis and other collagen diseases. Acta. Med. Scand. 184 (1968) 395–402.

    Google Scholar 

  102. Sapico, F. L., Emori, H., Smith, L. D. S., Bluestone, R., Finegold, S. M. Absence of relationship of fecalClostridium perfringens to rheumatoid arthritis and rheumatoid variants. J. Infect. Dis. 128 (1973) 539–562.

    Google Scholar 

  103. Cadham, F. T. A method of vaccine therapy in atrophic arthritis. Can. Med. Ass. J. 46 (1942) 31–34.

    Google Scholar 

  104. Hill, A. G. S., McCormick, J. N., Greenbury, C. L., Morris, C. J., Kenningdale, J. Cultivation of microorganisms from rheumatoid synovia. Ann. Rheum. Dis. 32 (1967) 319–325.

    Google Scholar 

  105. Bartholomew, L. E., Nelson, F. R. Corynebacterium acnes in rheumatoid arthritis. I. Isolation and antibody studies. Ann. Rheum. Dis. 31 (1972) 22–27.

    Google Scholar 

  106. Mardh, P. A., Nilsson, F. J., Bjelle, A. Mycoplasmas and bacteria in synovial fluid from patients with arthritis. Ann. Rheum. Dis. 32 (1973) 319–325.

    Google Scholar 

  107. Stewart, S. M., McBride, W. H. Mycoplasmas and diphtheroids in rheumatoid arthritis. In:Rotstein, T. (ed.): Rheumatology: An annual review. Karger, Basel, 1975, p. 329–337.

    Google Scholar 

  108. Clasener, H. A. L., Biersteker, P. J. Significance of diphtheroids isolated from synovial membranes of patients with rheumatoid arthritis. Lancet I (1969) 1031–1033.

    Google Scholar 

  109. Schwab, J. H. Biological properties of the chronic nodular lesion of connective tissue. J. Bacteriol. 90 (1965) 1405–1411.

    Google Scholar 

  110. Cromartie, W. J., Craddock, J. G.: Pathogenic action of group A streptococcal cellular components. Proc. Meet. Current Research Group A Streptococci, Paris, 1966, R. Caranario, Excerpta Medica Foundation, 1968, pp. 89–99.

  111. Cromartie, W. J. Pathogenic properties of streptococcal cell walls. In:Bowen, W. H., Genco, R. J., O'Brien, T. C. (ed.): Immunologic Aspects of Dental Caries. Information Retrieval Inc., Washington, D. C., 1976, pp. 183–185.

    Google Scholar 

  112. Pearson, C. M. Development of arthritis, peri-arthritis and periostitis in rats given adjuvants. Proc. Soc. Exp. Biol. Med. 91 (1956) 95–101.

    Google Scholar 

  113. Pearson, C. M., Wood, F. D. Passive transfer of adjuvant arthritis by lymph node or spleen cells. J. Exp. Med. 120 (1964) 547–560.

    Google Scholar 

  114. Waksman, B. H., Wennersten, C. Passive transfer of adjuvant arthritis in rats with living lymphoid cells of sensitized donors. Int. Arch. Allergy 23 (1963) 129–139.

    Google Scholar 

  115. Hadler, N. M. A pathogenetic model for erosive synovitis: lessons from animal arthritides. Arthritis Rheum. 19 (1976) 256–266.

    Google Scholar 

  116. Cromartie, W. J., Craddock, J. G., Schwab, J. H. Production of chronic arthritis in rats with Group A streptococcal cellular components. Fed. Proc. 27 (1968) 44 (abst.).

    Google Scholar 

  117. Heymer, B. Biological properties of the peptidoglycan. Z. Immunitätsforsch. 149 (1975) 245–257.

    Google Scholar 

  118. Schwab, J. H., Smialowicz, R. Interation of bacterial cell wall polymers and rat macrophages. Z. Immunitätsforsch. 149 (1975) 283–288.

    Google Scholar 

  119. Koga, T., Pearson, C. M. Immunogenicity and arthritogenicity in the rat of an antigen fromMycobacterium tuberculosis wax D. J. Immunol. 111 (1973) 599–608.

    Google Scholar 

  120. Ghuysen, J. M. Use of bacteriolytic enzymes in determination of wall structure and their role in cell metabolism. Bacteriol. Rev. 32 (1968) 425–464.

    Google Scholar 

  121. Schleifer, K. H., Kandler, O. Peptidoglycan type of bacterial walls and their taxonomic implications. Bacteriol. Rev. 36 (1972) 407.

    Google Scholar 

  122. Schleifer, K. H. Chemical structure of the peptidoglycan, its modifiability and relation to the biological activity. Z. Immunitätsforsch. 149 (1975) 104–117.

    Google Scholar 

  123. Davies, P., Page, R. C., Allison, A. C. Changes in cellular enzyme levels and extracellular release of lysosomal acid hydrolases in macrophages exposed to group A streptococcal cell wall substance. J. Exp. Med. 139 (1974) 1262–1282.

    Google Scholar 

  124. Harris, E. D. Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis. Arthritis Rheum. 19 (1976) 68–72.

    Google Scholar 

  125. Stewart-Tull, D. E. S., Shimono, T., Kotani, S., Kato, M., Ogawa, Y., Yamamura, Y., Koga, T., Pearson, C. M. The adjuvant activity of a non-toxic, water-soluble glycopeptide present in large quantities in the culture filtrate ofMycobacterium tuberculosis strain DT. Immunology 29 (1975) 1–15.

    Google Scholar 

  126. Kohashi, O., Pearson, C. M., Watanabe, Y., Kotani, S., Koga, T. Structural requirements for arthritogenicity of peptidoglycans fromStaphylococcus aureus andLactobacillus plantarum and analogous synthetic compounds. J. Immunol. 116 (1976) 1635–1639.

    Google Scholar 

  127. Kotani, S., Narita, T., Stewart-Tull, D. E. S., Shimono, T., Watanabe, Y., Kato, K., Iwata, S. Immunoadjuvant activities of cell walls and their water-soluble fractions prepared from various Gram-positive bacteria. Biken J. 18 (1975) 77–92.

    Google Scholar 

  128. Kotani, S., Watanabe, Y., Narita, T., Shimono, T., Stewart-Tull, D. E. S., Iwata, S., Yamaguchi, H., Iwata, K., Shimizu, T., Mifuchi, I., Nozawa, Y., Ito, Y., Kanetsuna, F., Yano, K., Misaki, A., Matsuoka, T., Fukui, K. Immunoadjuvant activities of fungal cell walls. Biken J. 18 (1975) 135–138.

    Google Scholar 

  129. Kotani, S., Watanabe, Y., Shimono, T., Kinoshita, F., Narita, T., Kato, K., Stewart-Tull, D. E. S., Morisaki, I., Yokogawa, K., Kawata, S. Immunoadjuvant activities of peptidoglycan subunits from the cell walls ofStaphylococcus aureus andLactobacillus plantarum. Biken J. 18 (1975) 93–103.

    Google Scholar 

  130. Ellouz, F., Adam, A., Diobaru, F., Ledered, E. Minimal structural requirements for adjuvant activity of bacterial peptidoglycan derivatives. Biochem. Biophys. Res. Commun. 59 (1974) 1317–1325.

    Google Scholar 

  131. Kotani, S., Watanabe, Y., Shimono, T., Harada, K., Shiba, T., Kusumoto, S., Yokogawa, K., Taniguchi, M. Correlation between the immunoadjuvant activities and pyrogenicities of synthetic N-acetylmuramylpeptides or -amino acids. Biken J. 19 (1976) 9–13.

    Google Scholar 

  132. Rolicka, M., Park, J. T. Antimucopeptide antibodies and their specificity. J. Immunol. 103 (1969) 196–203.

    Google Scholar 

  133. Schliefer, K. H., Krause, R. M. The immunochemistry of peptidoglycan. I. The immunodominant site of the peptide subunit and the contribution of each of the amino acids to the binding properties of the peptides. J. Biol. Chem. 246 (1971) 986–993.

    Google Scholar 

  134. Karakawa, W. W., Maurer, P. H., Walsh, P., Krause, R. M. The role of D-alanine in the antigenic specificity of bacterial mucopeptides. J. Immunol. 104 (1970) 230–237.

    Google Scholar 

  135. Krause, R. M. Immunological activity of the peptidoglycan. Z. Immunitätsforsch. 149 (1975) 136–150.

    Google Scholar 

  136. Helgeland, S. M., Grov, A. Immunochemical characterization of staphylococcal and micrococcal mucopeptides. Acta Path. Microbiol. Scand. Sect. B 79 (1971) 819–826.

    Google Scholar 

  137. Schachenmayr, W., Heymer, B., Haferkamp, O. Antibodies to peptidoglycan in the sera from population surveys. Z. Immunitätsforsch. 149 (1975) 179–186.

    Google Scholar 

  138. Heymer, B., Schleifer, K. H., Read, S., Zabriskie, J. B., Krause, R. M. Detection of antibodies to bacterial cell wall peptidoglycan in human sera. J. Immunol. 117 (1976) 23–26.

    Google Scholar 

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  1. Department of Pathology, College of Medicine, University of Iowa, 52242, Iowa City, Iowa, USA

    E. Wilkes &  E. S. Meek

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  1. E. Wilkes
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For Part I see INFECTION 7 (1979) 125–128

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Wilkes, E., Meek, E.S. Rheumatoid arthritis: Review of searches for an infectious cause. Part II. Infection 7, 192–197 (1979). https://doi.org/10.1007/BF01640944

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