Abstract
This report describes the successful treatment of quadruple cancer including Bowen's disease in a 71-year-old man who had been given injections of salvarsan, an arsenic compound, for syphilis more than 40 years earlier. Resection of a skin lesion on his chest subsequently confirmed a diagnosis of Bowen's disease, 3 years after which he was operated on for concurrent gastric cancer and sigmoid colon cancer. A fourth cancer was discovered on his left vocal cord 2 weeks after this operation; it was resected 2 years later. A discussion of multiple malignant neoplasms and the possible relationship between arsenic and cancer is presented following this case report.
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Murata, K., Iwazawa, T., Takayama, T. et al. Quadruple cancer including bowen's disease after arsenic injections 40 years earlier: Report of a case. Surg Today 24, 1115–1118 (1994). https://doi.org/10.1007/BF01367469
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DOI: https://doi.org/10.1007/BF01367469