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Failure to demonstrate altered gastric emptying in irritable bowel syndrome

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Abstract

In irritable bowel syndrome (IBS), abnormalities of motility have been observed in the esophagus and small bowel, as well as in the colon. In order to investigate gastric function, gastric emptying has been measured in 25 patients with strictly defined IBS and compared with 25 age-and sex-mathched controls. A standard radioisotope method for measuring gastric emptying has been employed. There was no significant difference between the two groups (T1/2 gastric emptying, IBS subjects 99.3±9.4 min, control subjects 104.0±11.9 min, mean±sem), nor was there any major correlation between different symptom patterns and altered gastric emptying times. The results of the present investigation suggest that future studies on abnormalities in IBS should investigate other aspects of gastric motor function.

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Authors and Affiliations

  1. Department of Medicine H, Level D, S. Laboratory & Pathology Block, Southampton General Hospital, Tremona Rd., SO9 4XY, Southampton, UK

    U. Acharya (Professorial), N. Waite (Professorial), P. Howlett PhD (Professorial), A. R. Tanner DM (Professorial) &  C. L. Smith MD (Professorial)

  2. Department of Nuclear Medicine, Southampton General Hospital, Southampton, UK

    U. Acharya (Professorial), N. Waite (Professorial), P. Howlett PhD (Professorial), A. R. Tanner DM (Professorial) &  C. L. Smith MD (Professorial)

Authors
  1. U. Acharya
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  2. N. Waite
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  3. P. Howlett PhD
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  4. A. R. Tanner DM
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  5. C. L. Smith MD
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Acharya, U., Waite, N., Howlett, P. et al. Failure to demonstrate altered gastric emptying in irritable bowel syndrome. Digest Dis Sci 28, 889–892 (1983). https://doi.org/10.1007/BF01317038

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  • DOI: https://doi.org/10.1007/BF01317038

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