Summary
The ability to utilize siderophores of bacterial and fungal origin has been studied in wild-type and mutant strains of the enterobacterial generaSalmonella, Escherichia, Shigella, Moellerella, Klebsiella, Enterobacter, Hafnia, Pantoea, Ewingella, Tatumella, Yersinia, and in the non-entericsAeromonas, Pseudomonas andAureobacterium. Although only a few representative strains were tested, the results show characteristic genus-specific differences in the utilization of hydroxamate and catecholate siderophores. Moreover, the different response to structural alterations of certain siderophore classes by some wild-type and mutant strains points to variable interacting receptor domains.
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Barghouthi S, Young R, Arceneaux JEL, Byers BR (1989) Physiological control of amonabactin biosynthesis inAeromonas hydrophila. Biol Metals 2:155–160
Barghouthi S, Payne S, Arceneaux J, Byers R (1990) Cloning and mutagenesis of an Aeromonas hydrophila siderophore gene. Abstract, 2nd International Symposium on Iron Transport, Storage and Metabolism, University of Texas, Austin
Berner I, Konetschny-Rapp S, Jung G, Winkelmann G (1988) Characterization of ferrioxamine E as the principal siderophore ofErwinia herbicola (Enterobacter agglomerans). Biol Metals 1:51–56
Berner I, Winkelmann G (1990) Ferrioxamine transport mutants and the identification of the ferrioxamine receptor protein FoxA inErwinia herbicola (Enterobacter agglomerans). Biol Metals 2:197–202
Berner I, Yakirevitch P, Libman J, Shanzer A, Winkelmann G (1991) Chiral linear hydroxamates as biomimetic analogues of ferrioxamine and coprogen and their use in probing siderophore receptor specificity in bacteria and fungi. Biol Metals 4:186–191
Bitter W, Marugg JD, deWeger LA, Tommassen J, Weisbeek PJ (1991) The ferric-pseudobactin receptor PupA ofPseudomonas putida WCS358: homology to TonB-dependentEscherichia coli receptors and specificity of the protein. Mol Microbiol 5:647–655
Bossier P, Verstraete W (1986a) Detection of siderophores in soil by a direct bioassay. Soil Biol Biochem 18:482–487
Bossier P, Verstraete W (1986b) Ecology ofArthrobacter-JG9-detectable hydroxamate siderophores in soils. Soil Biol Biochem 18:487–492
Braun V (1981)Escherichia coli cells containing the plasmid ColV produce the iron ionophore aerobactin. FEMS Microbiol Lett 11:225–228
Braun V, Günter K, Hantke K (1991) Transport of iron across the outer membrane. Biol Metals 4:14–22
Braun V, Hantke K, Stauder W (1977) Identification of the Sid outer membrane receptor protein inSalmonella typhimurium SL1027. Mol Gen Genet 155:227–229
Carbonetti N, Williams PH (1984) A cluster of five genes specifying the aeropbactin iron uptake system of plasmid ColV-K30. Infect Immun 46:7–12
Emery T (1986) Exchange of iron by gallium in siderophores. Biochemistry 25:4629–4633
Gavini F, Mergaert J, Beji A, Mielcarek C, Izard D, Kersters K, De Ley J (1989) Transfer ofEnterobacter agglomerans (Beijerinck 1988) Ewing and Five 1972 to Pantoea gen. nov. asPantoea agglomerans comb. nov. and description ofPantoea dispersa sp. nov. Int J Syst Bacteriol 39:337–345
Hall RM, Ratledge C (1987) Exochelin-mediated iron acquisition by the leprosy bacillus,Mycobacterium leprae. J Gen Microbiol 133:193–199
Hall RM, Sritharan M, Messenger AJM, Ratledge C (1987) Iron transport inMycobacterium smegmatis: occurrence of iron-regulated envelope proteins as potential receptors for iron uptake. J Gen Microbiol 133:2107–2114
Hancock REW, Hantke K, Braun V (1977) Iron transport inEscherichia coli K12. 2,3-Dihydroxybenzoate-promoted iron uptake. Arch Microbiol 114:231–239
Hantke K (1990) Dihydroxybenzoylserine — a siderophore forE. coli. FEMS Microbiol Lett 67:5–8
Hartmann A, Braun V (1979) Uptake and conversion of the antibiotic albomycin byEscherichia coli K12. Eur J Biochem 99:517–524
Heesemann J (1987) Chromosomal-encoded siderophores are required for mouse virulence of enteropathogenicYersinia species. FEMS Microbiol Lett 48:229–233
Hohnadel D, Meyer J-M (1988) Specificity of pyoverdine-mediated iron uptake among fluorescentPseudomonas strains. J Bacteriol 170:4865–4873
Konetschny-Rape S, Jung G, Huschka H, Winkelmann G (1988) Isolation and identification of the principal siderophore of the plant pathogenic fungusBotrytis cinerea. Biol Metals 1:90–98
Konetschny-Rape S, Jung G, Meiwes J, Zähner H (1990) Staphyloferrin A: a structurally new siderophore from staphylococci. Eur J Biochem 191:65–74
Köster W (1991) Iron(III) hydroxamate transport across the cytoplasmic membrane ofEscherichia coli. Biol Metals 4:23–32
Kunze B, Bedorf N, Kohl W, Höfle G, Reichenbach H (1989) Myxochelin A, a new iron-chelating compound fromAngiococcus disciformis (Myxobacteriales). J Antibiot 42:14–17
Liu PV, Shokrani F (1978) Biological activities of pyochelins: iron-chelating agents ofPseudomonas aeruginosa. Infect Immun 22:878–890
Lawlor KM, Payne SM (1984) Aerobactin genes inShigella spp. J Bacteriol 160:266–272
Lochhead AG, Burton MO (1956) Incidence in soil of bacteria requiring vitamin B12 and the terregens factor. Soil Sci 82:237–245
Luckey M, Pollack JR, Wayne R, Ames BN, Neilands JB (1972) Iron uptake inSalmonella typhimurium: utilization of exogenous siderochromes as iron carriers. J Bacteriol 111:731–738
Meyer JM, Abdallah MA (1980) The siderochromes of non-fluorescent pseudomonads: production of nocardamine byPseudomonas stutzeri. J Gen Microbiol 130:1893–1910
Moore RE, Emery T (1976)N α-Acetylfusarinines: isolation, characterization and properties. Biochemistry 15:2719–2723
Mullis KB, Pollack JR, Neilands JB (1971) Structure of shizokinen an iron transport compound fromBacillus megaterium. Biochemistry 10:4894–4898
Müller G, Raymond KN (1984) Specificity and mechanism of ferrioxamine-mediated iron transport inStreptomyces pilosus. J Bacteriol 160:304–312
Payne S (1988) Iron and virulence in the family Enterobacteriaceae. CRC Crit Rev Microbiol 16:81–111
Pollack JR, Ames BN, Neilands JB (1970) Iron transport inSalmonella typhimurium: mutants blocked in the biosynthesis of enterobactin. J Bacteriol 104:635–639
Poole K, Young L, Neshat S (1990) Enterobactin-mediated iron transport inPseudomonas aeruginosa. J Bacteriol 172:6991–6996
Powell PE, Cline GR, Reid CPP, Szaniszlo PJ (1980) Occurrence of hydroxamate siderophore iron chelators in soils. Nature 287:833–834
Rabsch W, Tkacik J, Lindemann W, Mikula I, Reissbrodt R (1991) Different systems for iron supply ofSalmonella typhimurium andEscherichia coli wild strains as tool for typing. Zbl Bakt 274:437–445
Reissbrodt R, Rabsch W, Chapeaurouge A, Jung G, Winkelmann G (1990) Isolation and identification of ferrioxamine G and E inHafnia alvei. Biol Met 3:54–60
Sritharan M, Ratledge C (1990) Iron regulated envelope proteins of mycobacteria grown in vitro and their occurence inMycobacterium avium andMycobacterium leprae grown in vivo. Biol Metals 2:203–208
Tuffano TP, Raymond KN (1981) Coordination chemistry of microbial iron transport compounds. 21. Kinetics and mechanism of iron exchange in hydroxamate siderophore complexes. J Am Chem Soc 103:6617–6624
Williams P, Smith MA, Stevenson P, Griffith E, Tomas JMT (1989) Novel aerobactin receptor inKlebsiella pneumoniae. J Gen Microbiol 135:3173–3181
Winkelmann G, Braun V (1981) Stereoselective recognition of ferrichrome by fungi and bacteria. FEMS Microbiol Lett 11:237–241
Winkelmann G, van der Helm D, Neilands JB (1987) Iron transport in microbes, plants and animals. VCH Verlagsgesellschaft, Weinheim
Winkelmann G (1991) Handbook of microbial iron chelates. CRC Press Inc., Boca Raton
Wong GB, Kappet MJ, Raymond KN, Matzanke B, Winkelmann G (1983) Coordination chemistry of microbial iron transport compounds. 24. Characterization of coprogen and ferricrocin, two ferric hydroxamate siderophores. J Am Chem Soc 105:810–815
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Rabsch, W., Winkelmann, G. The specificity of bacterial siderophore receptors probed by bioassays. Biol Metals 4, 244–250 (1991). https://doi.org/10.1007/BF01141188
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DOI: https://doi.org/10.1007/BF01141188