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Production of L-lysine by free and PVA-cryogel immobilizedCorynebacterium glutamicum cells

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Summary

Free and immobilized cells ofC. glutamicum were analyzed for production of L-lysine. Non-growing free cells as well as immobilized ones produced higher levels of lysine than growing free cells, when cultured for 24 h in a medium containing 80 g/L glucose as a carbon source. The effect of initial biomass and yeast extract concentrations was investigated in order to improve lysine production.

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References

  • Hirose, Y., and Okada, H. (1979). Microbial production of amino acids. In: Microbial technology, H. J. Peppler and D. Perlman, eds. vol. 1, pp. 211–227, London: Academic Press.

    Google Scholar 

  • Kim, H.S., and Ryu, D.D.Y. (1982)Biotechnol. Bioeng. 24, 2167–2174.

    Google Scholar 

  • Lozinsky, V.I., Domotenko, L.V., Vainerman, E.S., Mamtis, A.M., Titova, E.F., Belavtseva, E.M., and Rogozhin, S.V. (1986a)Colloid Polymer Sci. 264, 19–24.

    Google Scholar 

  • Lozinsky, V.I., Vainerman, E.S., Rogozhin, S.V. USSR Patent 1400071 (1986 b).

  • Lozinsky, V.I., Faleev, N.G., Zubov, A.L., Ruvinov, S.V., Antonova, T.V., Vainerman, E.S., Belikov, V.M., and Rogozhin, S.V. (1989)Biotechnol. Lett. 11, 43–48.

    Google Scholar 

  • Nasri, M., Dhouib, A., Zorguani, F., Kriaa, H., and Ellouz, R. (1989)Biotechnol. Lett. 11, 865–870.

    Google Scholar 

  • Simonian, A.L., Tatikian, S.S., Khachatrian, G.E., Avakian, T.M., and Badalian, I.E. (1991)Biosensors and Bioelectronics 6, 93–96.

    Google Scholar 

  • Slowinski, W., and Charm, S.E. (1973)Biotechnol. Bioeng. 15, 973–979.

    Google Scholar 

  • Tanaka, T., Yamamoto, K., Towprayoon, S., Nakajima, H., Sonomoto, K., Yokozeki, K., Kubota, K., and Tanaka, A. (1989)Appl. Microbiol. Biotechnol. 30, 564–568.

    Google Scholar 

  • Terasawa, M., Inui, M., Goto, M., Shicata, K., Imanari, M., and Yukawa, H. (1990)J. Ind. Microbiol. 5, 289–294.

    Google Scholar 

  • Thore, A. (1981) Chemiluminescent analysis in microbiology. Technical Information Wallac Oy., 48 p. Helsinki: Frenckellin Kirjaipaino Oy.

    Google Scholar 

  • Ugarova, N.N., Brovko, L.Y., and Kost, N.V. (1982)Enzyme Microbiol. Technol. 4, 224–228.

    Google Scholar 

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Authors and Affiliations

  1. Department of Chemical Enzymology, Chemical Faculty, M. V. Lomonosov Moscow University, 119899, Moscow, Russia

    S. G. Velizarov, E. I. Rainina, A. P. Sinitsyn & S. D. Varfolomeyev

  2. Institute of Food Substances, Academy of Sciences of Russia, Vavilov str. 28, 117813, Moscow, Russia

    V. I. Lozinsky & A. L. Zubov

Authors
  1. S. G. Velizarov
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  2. E. I. Rainina
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  3. A. P. Sinitsyn
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  4. S. D. Varfolomeyev
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  5. V. I. Lozinsky
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  6. A. L. Zubov
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Velizarov, S.G., Rainina, E.I., Sinitsyn, A.P. et al. Production of L-lysine by free and PVA-cryogel immobilizedCorynebacterium glutamicum cells. Biotechnol Lett 14, 291–296 (1992). https://doi.org/10.1007/BF01022326

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  • DOI: https://doi.org/10.1007/BF01022326

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