Summary
The effect of sleep on the serum levels of hormones during prolonged heavy physical strain and calorie deficiency were investigated in 19 young men participating in a 5 day ranger training course with a calorie consumption of 35,000–50,000 kJ·24 h−1, and a calorie intake of about 6,000 kJ·24 h−1. The subjects were divided into two groups: the stress group (8 cadets) were allowed no organized sleep during the course, whereas the sleep group (9 cadets) had 3 h sleep each night.
Small but significantly (p<0.01) higher serum levels were found in the sleep group compared to the stress group for cortisol, growth hormone and testosterone. No such differences were found for catecholamines, androstendione, dihydrotestosterone, LH, triiodothyronine and thyroxine.
Androstendione and dihydrotestosterone decreased in parallel with testosterone (r=0.5) during the course, changes which directly or indirectly seem to be due to decreased testicular secretion. The changes found during this investigation for the other hormones are similar to changes found during previous courses. LH showed only small variation during the course and cannot explain the decreased secretion from the testis or the difference between the two groups for testosterone. All hormones were normal within 23 days after the end of the course.
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References
Aakvaag A, Bentdal Ø, Quigstad K, Walstad P, RØnningen H, Fonnum F (1978a) Testosterone and testosterone binding globulin (TeBG) in young men during prolonged stress. In J Androl 1: 22–31
Aakvaag A, Sand T, Opstad PK, Fonnum F (1978b) Hormonal changes in young men during prolonged physical strain. Eur J Appl Physiol 39: 283–291
Adamson L, Hunter WM, Ogunremi OO, Oswald I, Percy-Robb IW (1974) Growth hormone increase during sleep after daytime exercise. J Endocrinol 62: 473–478
Adlercreutz H, HÄrkönen M, Kuoppasalmi K, Kosunen K, NÄveri H, Rehunen S (1976) Physical activity and hormones. Adv Cardiol 18: 144–157
Beck U, Marquetand D (1976) Effects of selective sleep deprivation on sleep-linked prolactin and growth hormone secretion. Arch Psychiat Nervenkrank 223: 35–44
Boyar RM (1978) Sleep related endocrine rythms. In: Reichlin S, Baldessarini RJ, Martin JB (eds) The hypothalamus. Raven Press, New York, pp 373–385
Chopra IJ, Williams DE, Orgiazzi J and Solomon DH (1975) Opposite effects of dexamethasone on serum concentrations of 3, 31,51-triiodothyronine (reverse T3) and 3,31,5-triiodothyronine (T3). J Clin Endocrinol Metab 41: 911–920
De Prada M, Zürcher G (1976) Simultaneous radioenzymatic determination of plasma and tissue adrenaline, nor-adrenaline and dopamine within the femtomole range. Life Sci 19: 1161–1174
Horne JA (1978) A review of the biological effects of total sleep deprivation in man. Biol Psychol 7: 55–102
Magrini G, Ebiner JR, Burckhardt P et al. (1976) Study on the relationship between plasma prolactin and androgen metabolism in man. J Clin Endocrinol Metab 43: 944–947
Opstad PK, Ekanger R, Nummestad M, Raabe N (1978) Performance, mood and clinical symptoms in men exposed to prolonged, severe physical work and sleep deprivation. Aviat Space Environ Med 49: 1065, 1073
Opstad PK, Aakvaag A, Rognum TO (1980) Altered hormonal response to short term bicycle exercise in young men after prolonged physical strain, caloric deficit and sleep deprivation. Eur J Appl Physiol 45: 51–62
Opstad PK, Aakvaag A (1982) The effect of a high calory diet on hormonal changes in young man during prolonged physical strain and sleep deprivation. Eur J Appl Physiol 46: 31–39
Opstad PK, Aaakvaag A (1981) Decreased serum levels of oestradiol, testosterone and prolactin during prolonged physical strain and sleep deprivation and the influence of a high calory diet. Eur J Appl Physiol 49: 343–348
Palmblad J, åkerstedt T, FrØberg J, Melander A, von Schenck H (1979) Thyroid and andrenpmedullary reaction during sleep deprivation. Acta Endocrinol 90: 233–239
Sassin JF, Frantz AG, Kapen S, Weitzman ED (1973) The nocturnal rise of human prolactin is dependent on sleep. J Clin Endocrinol Metab 37: 436–440
Tait JF, Horton R (1966) The in vivo estimation of blood production and interconversion rates of androstenedione and testosterone and the calculation of their secretion rates. In: Pincus G, Nakao T, Tait JF (eds) Steroid dynamics. Academic Press, New York London, pp 393–427
Vermeulen A, Ando S (1978) Prolactin and adrenal androgen secretion. Clin Endocrinol (Oxf) 8: 295–303
Weitzman ED, Boyar RM, Kapen S, Hellman L (1975) The relationship of sleep stages to neuroendocrine secretion and biological rythms in man. Rec Progr Hormone Res 31: 399–441
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Opstad, P.K., Aakvaag, A. The effect of sleep deprivation on the plasma levels of hormones during prolonged physical strain and calorie deficiency. Europ. J. Appl. Physiol. 51, 97–107 (1983). https://doi.org/10.1007/BF00952542
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DOI: https://doi.org/10.1007/BF00952542