Abstract
Tubulin content was immunohistochemically studied inEchinococcus granulosus protoscolices incubated with albendazole and albendazole sulphoxide alone or in combination. Tubulin immunoreactivity was very patent in the control protoscolices and was mainly located in the sucker region and the invagination channel of protoscolices. Treated protoscolices always showed less immunoreactivity than did control protoscolices. We concluded that albendazole and its metabolite albendazole sulphoxide produce tubulin alterations inE. granulosus protoscolices.
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Pérez-Serrano, J., Denegri, G., Casado, N. et al. Anti-tubulin immunohistochemistry study ofEchinococcus granulosus protoscolices incubated with albendazole and albendazole sulphoxide in vitro. Parasitol Res 81, 438–440 (1995). https://doi.org/10.1007/BF00931507
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DOI: https://doi.org/10.1007/BF00931507