Abstract
A retrospective review is presented of the medical records of seven female patients with uveitis associated with definite multiple sclerosis. Six of the patients had severe bilateral chronic granulomatous anterior uveitis, which in four cases resulted in extensive posterior synechiae and scarring of the peripupillary iris. One patient had bilateral intermediate uveitis with unilateral posterior synechiae. Severe chronic granulomatous anterior uveitis associated with multiple sclerosis has a predilection for women, can precede neurological symptoms and can be controlled with topical steroids.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Aracil P, Moyenin P, Ryckewaert M, Francoz-Taillanter N (1986) Pars planitis et sclerose en plaque. Bull Soc Ophthalmol Fr 86:485–487
Archambeau PL, Hollenhorst RW, Rucker CW (1965) Posterior uveitis as a manifestation of multiple sclerosis. Mayo Clin Proc 40:544–551
Arnold AC, Pepose JS, Helper RS, Foos RY (1984) Retinal periphlebitis and retinitis in multiple sclerosis, I. Pathologic characteristics. Ophthalmology 91:255–262
Bachman DM, Rosenthal AR, Beckingsale AB (1985) Granulomatous uveitis in neurological disease. Br J Ophthalmol 69:192–196
Bamford CR, Ganley JP, Sibley WA, Laguna JF (1978) Uveitis, perivenous sheathing and multiple sclerosis. Neurology 28:119–124
Breger BC, Leopold IH (1966) The incidence of uveitis in multiple sclerosis. Am J Ophthalmol 62:540–545
Graham EM, Francis DA, Sanders MD, Rudge P (1989) Ocular inflammatory changes in multiple sclerosis. J Neurol Neurosurg Psychiatry 52:1360–1363
Haarr M (1962) Uveitis with neurological symptoms. Acta Neurol Scand 38:171–187
Jabs DA, Johns CJ (1986) Ocular involvement in chronic sarcoidosis. Am J Ophthalmol 102:297–301
Lim JI, Tessler HH, Goodwin JA (1991) Anterior granulomatous uveitis in patients with multiple sclerosis. Ophthalmology 98:142–145
Matthews WB (1985) McAlpine's multiple sclerosis, Churchill Livingstone, New York, pp 6–7
Meisler DM, Tomsak RL, Khoury S, Hanson MR, Schwab IR, Ransohoff RM (1989) Anterior uveitis in multiple sclerosis. Cleve Clin J Med 56:535–538
Moller PM, Hammerberg PE (1963) Retinal periphlebitis in multiple sclerosis. Acta Neurol Scand 39:263–269
Porter R (1972) Uveitis in association with multiple sclerosis. Br J Ophthalmol 56:478–481
Poser CM, Paty DW, Scheinberg L, et al (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13:227–231
Younge BR (1976) Fluorescein angiography and retinal venous sheathing in multiple sclerosis. Can J Ophthalmol 11:31–36
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Acar, M.A., Birch, M.K., Abbott, R. et al. Chronic granulomatous anterior uveitis associated with multiple sclerosis. Graefe's Arch Clin Exp Ophthalmol 231, 166–168 (1993). https://doi.org/10.1007/BF00920941
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00920941