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Sensorineural hearing loss in patients reaching chronic renal failure in childhood

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Abstract

The incidence of sensorineural hearing loss (SNHL) was investigated in 68 patients who reached chronic renal failure (CRF) in childhood with the aim of identifying possible risk factors. Tests were carried out by means of pure-tone and impedance audiometry. SNHL was found in 29% of patients on conservative treatment, 28% of patients on hemodialysis, and 47% after renal transplantation. Differences among groups were not significant. A significant correlation was found with the administration of ototoxic drugs (aminoglycosides and furosemide). We hypothesize that SNHL may be reduced in patients with CRF or on renal replacement therapy by strictly monitoring ototoxic therapy.

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References

  1. Rizzoni G, Ehrich JHH, Broyer M, Brunner FP, Brynger H, Fassbinder W, Geerlings W, Selwood NH, Tufveson G, Wing AJ (1992) Rehabilitation of young adults during renal replacement therapy in Europe. Nephrol Dial Transplant 7: 573–578

    Google Scholar 

  2. Benninger C, Klack U, Mehls O, Pietz J, Soergel M, Shaerer K (1992) Evoked potentials (EP) in children with chronic renal failure (CRF). Proceedings of the 9th International Pediatric Nephrology Association Congress. Jerusalem, 30 Aug–4 Sept 1992. Published in Pediatr Nephrol 6 (5): C 180

    Google Scholar 

  3. Bureau International de Audiophonologie (1986) In: Pelisse JM, Puoyat PM Classification des dèficiences uditives. Encycl Med Chir Oto-Rhino-Laryngol 20190 (C20): 4

  4. Jerger S (1970): Clinical experience with impedence audiometry Arch Otolaryngol 92: 311–324

    Google Scholar 

  5. Trompeter R (1987) A review of prescribing in children with endstage renal failure. Pediatr Nephrol 4: 183–194

    Google Scholar 

  6. Gafter U, Shvili Y, Levi J, Talmi Y, Zohary Y (1989) Brainstem auditory evoked responses in chronic renal failure and the effect of hemodialysis. Nephron 53: 2–5

    Google Scholar 

  7. Oda M, Preciado M, Qiuck C, Paparella M (1974) Labyrinthine pathology of chronic renal failure patients treated with hemodialysis and kidney transplantation. Laryngoscope 84: 1489–1506

    Google Scholar 

  8. Bergstrom L, Jenkins P, Sando I, English GM (1973) Hearing loss in renal disease: clinical and pathological studies. Ann Otol Rhinol Laryngol 82: 555–576

    Google Scholar 

  9. Yassin A, Badry A, Fatt-Hi A (1970) The relationship between electrolyte balance and cochlear disturbances in cases of renal failure. J Laryngol Otol 84: 429–435

    Google Scholar 

  10. Fee WE Jr (1980) Aminoglycoside ototoxicity in the human. Laryngoscope 90: 1–19

    Google Scholar 

  11. Thompson P, Wood RP II, Bergstrom L (1980) Erythromycin Ototoxicity. J Otolaryngol 9: 60–92

    Google Scholar 

  12. Quick CA, Hoppe W (1974) Permanent deafness associated with furosemide administration. Ann Otol Rhinol Laryngol 84: 94–101

    Google Scholar 

  13. Quick CA, Fish A, Brown C (1973) The relationship between cochlea and kidney. Laryngoscope 83: 1469–1482

    Google Scholar 

  14. Antonelli AR, Bonfioli F, Garrubba V, Ghisellini M, Lamoretti MP, Nicolai P, Camerini C, Maiorca R (1991) Audiological findings in elderly patients with chronic renal failure. Acta Otolaryngol [Suppl] (Stockh) 476: 54–68

    Google Scholar 

  15. Marsh JT, Brown WS, Wolcott D (1986) Electrophysiological indices of CNS function in hemodialysis and CAPD. Kidney Int 30: 957

    Google Scholar 

  16. Kligerman AB, Solany KB, Ventry IM, Gooodman AI Wesley S (1981) Hearing impairment associated with chronic renal failure. Laryngoscope 91: 583–592

    Google Scholar 

  17. Mitschke H, Schmidt P, Kopsa H, Pils P (1977) Effect of renal transplantation on uremic deafness: a long term study. Audiology 16: 530–534

    Google Scholar 

  18. Prezant TR, Agapian JV, Bohlman, MC, Bu X, Oztas S, Qiu WQ, Arnos KS, Cortopassi GA, Jaber L, Rotter JT, Shohat M, Fishel-Ghodian N (1993) Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non syndromic deafness. Nature Genet 4: 289–294

    Google Scholar 

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Mancini, M.L., Strologo, L.D., Bianchi, P.M. et al. Sensorineural hearing loss in patients reaching chronic renal failure in childhood. Pediatr Nephrol 10, 38–40 (1996). https://doi.org/10.1007/BF00863438

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  • DOI: https://doi.org/10.1007/BF00863438

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