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Light microscopical demonstration and zonal distribution of parasinusoidal cells (Ito cells) in normal human liver

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Summary

The parasinusoidal cells of the liver (Ito cells) were demonstrated light microscopically in autopsy specimens fixed in formalin and stained with Oil red O after dichromate treatment. The method allows examination of large samples containing numerous acini.

Quantitative assessment showed a zonal gradient with 6.3 and 7.7 parasinusoidal cells per 62.5 × 103 µm2 in zone 1 and 3, respectively.

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Horn, T., Junge, J., Nielsen, O. et al. Light microscopical demonstration and zonal distribution of parasinusoidal cells (Ito cells) in normal human liver. Vichows Archiv A Pathol Anat 413, 147–149 (1988). https://doi.org/10.1007/BF00749676

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  • DOI: https://doi.org/10.1007/BF00749676

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