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Short stature: a common feature in Duchenne muscular dystrophy

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Abstract

In a retrospective growth evaluation, which included parental height, birth length and a longitudinal analysis of growth and bone maturation, it has been shown that short stature is a common finding in Duchenne muscular dystrophy already in an early or even preclinical stage. Normal length and weight at birth, slow subsequent growth with a curve crossing the centiles in the 1st years of life, and normal bone maturation are characteristic of this type of short stature.

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Abbreviations

DMD:

Duchenne muscular dystrophy

SD:

standard deviation

SDS:

standard deviation scores

SEM:

standard error of the mean

MP:

mean mid-parent height

M:

mean height of fathers (male)

F:

mean height of mothers (female)

Xp:

short arm of the X-chromosome

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Authors and Affiliations

  1. Department of Paediatrics, University of Zurich, Steinwiesstrasse 75, CH-8032, Zurich, Switzerland

    U. Eiholzer, E. Boltshauser, L. Molinari & M. Zachmann

  2. Institute of Medical Genetics, University of Zurich, Switzerland

    D. Frey

Authors
  1. U. Eiholzer
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  2. E. Boltshauser
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  3. D. Frey
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  4. L. Molinari
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  5. M. Zachmann
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Eiholzer, U., Boltshauser, E., Frey, D. et al. Short stature: a common feature in Duchenne muscular dystrophy. Eur J Pediatr 147, 602–605 (1988). https://doi.org/10.1007/BF00442472

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  • DOI: https://doi.org/10.1007/BF00442472

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