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In vitro acitivity of ribostamycin against Prototheca sp.

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Abstract

The in vitro activity of ribostamycin against algae of the genus Prototheca was evaluated by minimum inhibitory concentration (MIC) studies on solid media. Concentrations of 4 mcg/ml were required to inhibit 100% of the P. zopfii strains; 16 mcg/ml inhibited 100% of the P. stagnora strains and 95% of the P. wickerhamii strains. These values are inferior to plasma concentrations obtained after injection of ribostamycin. It is likely that this antibiotic could be effective in the treatment of protothecosis in man.

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Authors and Affiliations

  1. Department of Microbiology, School of Medicine, University of Cordoba, Cordoba, Spain

    Casal M. & Gutierrez Aroca J.

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  1. Casal M.
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  2. Gutierrez Aroca J.
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Casal, M., Gutierrez Aroca, J. In vitro acitivity of ribostamycin against Prototheca sp.. Mycopathologia 83, 21–23 (1983). https://doi.org/10.1007/BF00437408

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  • DOI: https://doi.org/10.1007/BF00437408

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