Summary
An ovarian epithelial tumour is described with a compound histological structure containing features of an androblastoma with well differentiated Sertoli-Leydig cell structures and features resembling a carcinoid tumour.
Scattered argyrophil cells were demonstrated in both components of the tumour. Neurohormonal peptides were found immunocytochemically in a minor fraction of the argyrophil cells. These included pancreatic polypeptide (PP), glucagon/enteroglucagon and enkephalin.
These findings indicate a high degree of multipotentiality of the progenitor cells of the neoplasm.
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This investigation was supported by grants from Sigrid Simonssons and Agni Olssons Fund, the Cancer Research Fund of Malmö General Hospital, the Medical Faculty at the University of Lund and the Swedish Research Council (Project No. 12X-718)
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Sporrong, B., Clase, L., Ljungberg, O. et al. Neurohormonal peptides and argyrophil cells in an androblastoma of the ovary. Virchows Arch. A Path. Anat. and Histol. 396, 239–246 (1982). https://doi.org/10.1007/BF00431245
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DOI: https://doi.org/10.1007/BF00431245