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l-Dopa effects on motor and “central programming” deficits in Parkinsonism

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Abstract

A study was made to test the effects of treatment by l-Dopa on both motor and “central programming” deficits in Parkinsonism.

Nine patients with Parkinsonism were tested on psychomotor tasks, involving both unimanual and bimanual performance, before and after treatment. Control data was obtained from 28 age-matched subjects. These were only tested on one occasion.

As expected, there was a very significant improvement in motor performance of the Parkinsonism group after treatment by l-Dopa. The evidence of improvement in the “central programming” deficit was less conclusive, but seemed substantial enough to warrant further investigation.

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Authors and Affiliations

  1. Department of Psychiatry, University of Melbourne Royal Melbourne Hospital, 3050, Victoria, Australia

    David J. de L. Horne

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  1. David J. de L. Horne
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de L. Horne, D.J. l-Dopa effects on motor and “central programming” deficits in Parkinsonism. Psychopharmacologia 36, 175–180 (1974). https://doi.org/10.1007/BF00421789

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  • DOI: https://doi.org/10.1007/BF00421789

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