Summary
Insulin effect was investigated in 20 chronic alcoholics by use of an insulin and glucose infusion which suppressed endogenous insulin secretion. It was found that the effect of insulin was lower during the first week than the second week of alcohol withdrawal.
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References
Deibert D, DeFronzo R (1980) Epinephrine induced insulin resistance in man. J Clin Invest 65: 717–721
DeFronzo RA, Ferrannine E, Hendler R, Wahren J, Felig P (1978) Influence of hyperinsulinaemia, hyperglycaemia and the route of glucose administration of splanchnic glucose exchange. Proc Natl Acad Sci USA 75: 5173–5177
Documenta Geigy (1962) Scientific tables, 6th edn. JR Geigy, Basle, p 624
Kahn CR (1980) Role of insulin receptors in insulin resistant states. Metabolism 29: 455–466
Marks V (1978) Alcohol and carbohydrate metabolism. Clin Endocrinol Metab 7: 333–349
Persson B (1969) Determination of plasma acetoacetate and D-β-hydroxybutyrate in new-born infants by an enzymatic florometric micromethod. Scand J Clin Lab Invest 25: 9–18
Phillips GB, Safrit HF (1971) Alcoholic diabetes. J Am Med Assoc 217: 1513–1519
Sacca L, Hendler R, Sherwin RS (1978) Hyperglycaemia inhibits glucose production in man independent of changes in glucoregulatory hormones. J Clin Endocrinol Metab 47: 1160–1163
Shen SW, Reaven GM, Farquhar JW (1970) Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest 49: 2151–2160
Soeldner JS, Slone D (1965) Critical variables in the radio immunoassay of serum insulin using the double antibody technic. Diabetes 14: 771–779
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Adner, N., Nygren, A. Insulin effect in chronic alcoholics during alcohol withdrawal. Diabetologia 22, 215–216 (1982). https://doi.org/10.1007/BF00283756
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DOI: https://doi.org/10.1007/BF00283756