Summary
The chromosomal constitution and DNA distribution of transitional cell bladder carcinoma were examined by karyotyping and flow cytometry in 16 patients. In tumours of low grade malignancy (grades I and II) the cell population was mainly diploid and marker chromosomes were present only occasionally. Grade III tumours were polyploid in all but one instance and marker chromosomes were constantly found. The DNA distribution was in good agreement with karyotyping data. These two methods may be regarded as complementary in the cytogenetic assessment of bladder tumours.
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Granberg-Öhman, I., Tribukait, B., Wijkström, H. et al. Papillary carcinoma of the urinary bladder. Urol. Res. 8, 87–93 (1980). https://doi.org/10.1007/BF00271434
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DOI: https://doi.org/10.1007/BF00271434