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Degenerative changes after meniscectomy and meniscal regeneration

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Summary

In an experimental study on rabbit knees, regeneration of the medial meniscus occurred following 9 out of 10 meniscectomies, compared with only 1 out of 10 lateral menisci. Degenerative changes in the articular cartilage were seen in 8 of 9 knees where the lateral cartilage failed to regenerate, but in only 2 of 9 with a regenerated medial cartilage. The rate of regeneration is lower after lateral meniscectomy and this may partially explain the occurrence of more severe degenerative changes after this operation.

Résumé

Dans une étude expérimentale portant sur l'articulation du genou chez le lapin, on a constaté que le ménisque interne régénère 9 fois sur 10 après méniscectomie, alors que l'externe ne se reconstitue qu'une fois sur 10. On observe des lésions dégénératives du cartilage articulaire 8 fois sur 9 en l'absence de régénération du ménisque externe contre seulement 2 sur 9 lorsque le ménisque interne s'est reconstitué. La régénération est donc moins fréquente après méniscectomie externe, ce qui peut expliquer en partie la survenue de lésions dégénératives plus marquées après cette intervention.

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Moon, MS., Chung, IS. Degenerative changes after meniscectomy and meniscal regeneration. International Orthopaedics 12, 17–19 (1988). https://doi.org/10.1007/BF00265736

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