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Precise localization on chromosome 12 of the ATF-1 gene by fluorescence in situ hybridization

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Abstract

The ATF-1 gene encodes for a transcription factor normally regulated by cAMP (Hai et al. 1989, Yoshimura et al. 1990). Recently, it has been shown to be involved in the recurrent t(12;22) translocation observed in soft tissue malignant melanoma, in a fusion gene with the EWS gene (Zucman et al. 1993). We report here on its precise localization on chromosome 12 by fluorescence in situ hybridization.

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Desmaze, C., Zucman, J., Delattre, O. et al. Precise localization on chromosome 12 of the ATF-1 gene by fluorescence in situ hybridization. Hum Genet 93, 207–208 (1994). https://doi.org/10.1007/BF00210613

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  • DOI: https://doi.org/10.1007/BF00210613

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