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Allogenic decalbone in the repair of benign cystic lesions of bone

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Summary

Forty-six cases of benign cystic lesions of bone were treated by curettage and compact filling using partially decalcified allogenic bone graft (Decalbone); of these, 35 were available for study. Decalbone was prepared by partial decalcification with 0.6 N hydrochloric acid (HCl) of human bones generally obtained from freshly amputated limbs. The commonest lesions of bone were giant cell tumours (14) and aneurysmal bone cysts (15), and the commonest bones involved were the femur (23) and the tibia (12). There was one failure and four recurrences. Five cases were infected but this did not interfere with healing of the primary lesion. Radiological incorporation of the graft was seen at about 3 months in unicameral bone cysts, at 4–6 months in aneurysmal bone cysts and at 6–9 months in giant cell tumours. There was no recurrence in any case of giant cell tumour, but three aneurysmal bone cysts recurred. There was no clinical immune reaction.

Résumé

Le «décalbone» est préparé par décalcification partielle (par NHCl) d'os humain, généralement obtenu à partir de pièces d'amputation fraîches. Il est ensuite conservé dans l'éthanol à 80–90° dans un réfrigérateur ordinaire, jusqu'à utilisation. 46 malades, porteurs de lésions kystiques bénignes, 14 tumeurs à cellules géantes (TCG), 15 kystes anévrysmaux, 6 kystes essentiels, 9 dysplasies fibreuses et 2 fibromes ossifiants, ont été traités par curetage et comblement à l'aide de décalbone allogène. Les os les plus fréquemment atteints étaient le fémur (23 fois) et le tibia (12 fois). Il y a en un échec et quatre récidives. Cinq infections sont survenues, qui n'ont pas empêché la guérison de la lésion initiale. L'incorporation radiologique de la greffe a été visible aux environs du 3ème mois dans les kystes essentiels, entre 4 et 6 mois dans les kystes anévrysmaux et entre 6 et 9 mois dans les TCG. Il n'y a eu aucune récidive dans les TCG, mais 3 dans les kystes anévrysmaux. On n'a pas observé de réaction clinique de rejet. Dans l'ensemble les résultats peuvent être favorablement comparés à ceux des allogreffes conservées dans des banques d'os sophistiquées.

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Authors and Affiliations

  1. Department of Orthopaedics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    S. C. Goel, S. M. Tuli, H. P. Singh, S. V. Sharma, S. K. Saraf & T. P. Srivastava

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  1. S. C. Goel
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  2. S. M. Tuli
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  3. H. P. Singh
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  4. S. V. Sharma
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  5. S. K. Saraf
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  6. T. P. Srivastava
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Goel, S.C., Tuli, S.M., Singh, H.P. et al. Allogenic decalbone in the repair of benign cystic lesions of bone. International Orthopaedics 16, 176–179 (1992). https://doi.org/10.1007/BF00180212

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