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Apoprotein B in subretinal fluid

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Abstract

We studied the presence of apolipoprotein B (apo B) by immunoelectrophoresis in subretinal fluid (SRF) and serum from 15 rhegmatogenous retinal detachments and 5 retinal detachments with proliferative vitreoretinopathy (PVR). Apo B concentration ± standard deviation was 1.49 ± 1.06 mg/dl in SRF and 108.41 ± 40.22 mg/dl in serum. Only in four cases was apo B not detected in SRF. We found no significant correlation between apo B concentrations in SRF and apo B levels in serum. We did not find a positive correlation between apo B concentrations in SRF and the duration and size of the detachments. There was no statistical relationship between the presence of PVR and apo B levels. This phenomenon suggests the preservation of the outer blood retinal barrier during rhegmatogenous retinal detachment.

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Huerva, V., Sinués, B., Canto, L.M. et al. Apoprotein B in subretinal fluid. Int Ophthalmol 20, 181–185 (1996). https://doi.org/10.1007/BF00175257

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