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Immunotoxicology and Risk Assessment

  • Book
  • © 1999

Overview

Authors:
  1. Dennis K. Flaherty

    1. St. Louis

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Introduction to Immunotoxicology

    Pages 1-6

  3. Innate Immunity

    Pages 7-13

  4. Cells of the Immune System

    Pages 15-37

  5. Immunogenicity and Antigenicity

    Pages 39-49

  6. Antigen-Presenting Cells

    Pages 51-56

  7. Antigen Presentation

    Pages 57-70

  8. Surface Interactions and Intracellular Signaling

    Pages 71-88

  9. B-Cell Activation

    Pages 89-97

  10. Antibodies

    Pages 99-115

  11. Immunological Memory

    Pages 117-122

  12. Complement

    Pages 123-137

  13. Phagocytosis and Intracellular Killing

    Pages 139-153

  14. Immediate Hypersensitivity Reactions

    Pages 155-171

  15. Autoimmunity

    Pages 173-186

  16. Delayed Hypersensitivity Reactions

    Pages 187-195

  17. Killer Cells

    Pages 197-209

  18. Killer Cells and Viral Infections

    Pages 211-218

  19. Transplantation

    Pages 219-227

  20. The Kines

    Pages 229-245
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Keywords

About this book

This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to toxicologists because it will incorporate new guidelines that the EPA is bringing out later this year for all chemicals regulated under the Federal Insecticide, Fungicide, and Rodenticide Act and the Toxic Substances Control Act. Regulatory sections in each chapter focus on data from both the US Food and Drug Administration, as well as data applicable to western European Nations.

Authors and Affiliations

  • St. Louis

    Dennis K. Flaherty

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