Abstract
The stability constants for the binary M(II)- chlorpromazine hydrochloride (CPZ) and the ternary complexes M(II)-chlorpromazine-amino acid, have been studied using pH-measurements. The amino acids (aa) are: glycine, glutamic acid, histidine and the metal ions are: Cu(II), Zn(II), Co(II), Ni(II) and UO2(II). All experiments were carried out in the presence of 0.1 mol dm−3 KNO3. The resulting stability constants of the binary and the ternary complexes were compared. It was observed that the stability of the ternary complexes-except for glutamic acid – are lower than of the binary ones.
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Received October 22, 1998. Revision March 14, 1999.
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Khodari, M. Electrometric Studies on the Ternary Complexes of M(II) With Chlorpromazine and Some Amino Acids. Mikrochim Acta 131, 231–235 (1999). https://doi.org/10.1007/PL00013457
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DOI: https://doi.org/10.1007/PL00013457