Abstract
Interscapular brown adipose tissue was studied in pregnant and lactating females and compared with virgin females in inbred Wistar rats, using the histomorphology and quantitation of cell numbers. In pregnant females an increase in the interscapular brown adipose tissue weight, total fat content and total fat cell numbers associated with a decrease in adipocyte diameter was observed when compared with virgin females. The total lipid content and total fat cell number in the interscapular brown adipose tissue of lactating females showed a decrease when compared to the pregnant females. This suggests that pregnancy and lactation are accompanied by changes in the status of interscapular brown adipose tissue which may be related to the changes in energy metabolism in these physiological states.
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References
Afzelius B A 1970 Brown adipose tissue: Its gross anatomy, histology and cytology; inBrown adipose tissue (ed.) O Lindberg New York: American Elsevier Pub. Co.) pp. 1–31
Agius L and Williamson D H 1980 Lipogenesis in IBAT of virgin, pregnant and lactating rats. The effects of intragastric feeding;Biochem. J. 190 477–480
Ashwell M, Priest P, Bondoux M and McPherson C K 1976 Human fat cell sizing—a quick, simple method;J. Lipid Res. 17 190–192
Cannolly E, Morrisey R D and Carnie J A 1982 The effect of interscapular brown adipose tissue removal on body weight and cold response in the mouse;Br. J. Nutr. 47 653–658
Folch J, Lees M and Sloane Stanley G H 1957 Extraction of total lipids from animal tissues;J. Biol. Chem. 226 497–509
Foster D O and Frydman M L 1978 Non-shivering thermogenesis in the rat. II Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline;Can. J. Physiol. Pharmacol. 56 110–122
Rothbard M J 1958Am. Midl. Nat. 59 2460cited in Brown Adipose Tissue (ed) O Lindberg (New York: American Elsevier Pub. Co.) p. 29
Rothwell N J and Stock M J 1981 Regulation of energy balance;Ann. Rev. Nutr. 1 235–256
Sims R A, Allen R and Sulkin S E 1962 Influence of pregnancy and cortisone on brown adipose tissue in bats;Proc. Soc. Exp. Biol. Med. 111 455–458
Teodoru C V and Grishman E 1959 Alterations of the interscapular brown fat (hibernating gland) during pregnancy in hamsters,Fed. Proc. 18 510
Trayhurn P, James W P T and Gurr M I 1979 Studies on the body composition, fat distribution, and fat cell size and number of ‘Ad’ a new obese mutant mouse;Br. J. Nutr. 41 211–221
Trayhurn P and James W P T 1981 inThe body weight regulatory system: Normal and disturbed mechanisms. (eds) L A Cioffi, W P T James and T B van Itallie (New York: Raven Press) pp. 97–105
Trayhurn P, Douglas J B and McGuckin M M 1982 Brown adipose tissue thermogenesis is ‘suppressed’ during lactating in mice;Nature (London) 298 59–60
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Dechamma, P.A., Kamath, S. & Shetty, P.S. Histomorphology, adipocyte size and total fat cell number in the interscapular brown adipose tissue of pregnant and lactating rats. Proc. Indian Acad. Sci. (Anim. Sci.) 95, 45–50 (1986). https://doi.org/10.1007/BF03179356
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DOI: https://doi.org/10.1007/BF03179356