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Evaluation of clinical methods in gastro-intestinal disease

II. Cholesterol determinations in peptic ulcer

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The American Journal of Digestive Diseases

Summary

A study to determine the possible relationship of cholesterol to peptic ulcer was made comparing the findings in 35 proven cases of peptic ulcer with 35 functional gastric cases.

No relationship between cholesterol levels and gastric acidity or blood glucose was found either in the ulcer or the functional cases. This lack of correlation, as well as the growing evidence for the causal relationship of cholesterol to arteriosclerosis and atherosclerosis speak against the use of high cholesterol diets in the treatment of peptic ulcer.

There appears to be no valid reason at present to routinely determine the cholesterol level in the study of a patient with peptic ulcer. Its usefulness is largely limited to gall bladder investigations.

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References

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Goldbloom, A.A., Lieberson, A. & Stamm, J.L. Evaluation of clinical methods in gastro-intestinal disease. A. J. D. D. 16, 313–315 (1949). https://doi.org/10.1007/BF03002731

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  • DOI: https://doi.org/10.1007/BF03002731

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