Abstract
Several analogues of the general formulae 2-methoxy-9-substituted acridine and 6-chloro-2-methoxy-9-substituted acridine were synthesized and evaluatedin vitro at 6.25 μg/mL againstM. tuberculosis H37Rv. Compounds15 and17 showed potential antitubercular activity with 100% inhibition to the virulent mycobacterium.
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Aly, E.I., Abadi, A.H. Synthesis and antitubercular activity of 6-chloro (unsubstituted)-2-methoxy-9-substituted acridine derivatives. Arch Pharm Res 27, 713–719 (2004). https://doi.org/10.1007/BF02980137
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DOI: https://doi.org/10.1007/BF02980137