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Structural analogues of cumambrin B from the flower ofChrysanthemum boreale

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Abstract

The structural analogues of cumambrin B (1, 2, 3, 4) were isolated from the flower ofChrysanthemum boreale Makino. The structures of compounds were determined by two-dimensional1H-1H COSY and13C-1H COSY spectra with the aid of homonuclear and heteronuclear double resonance experiment. The stereochemistry of compounds has been verified from single crystal X-ray diffraction of cumambrin A (2). The antimicrobial activities of these guaianolides have been studied.

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Authors and Affiliations

  1. Department of Agricultural Chemistry, Gyeongsang National University, 660-701, Chinju, Korea

    Dae Sik Jang, Min Suk Yang, Tae Jung Ha & Ki Hun Park

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  1. Dae Sik Jang
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  2. Min Suk Yang
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  3. Tae Jung Ha
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  4. Ki Hun Park
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Jang, D.S., Yang, M.S., Ha, T.J. et al. Structural analogues of cumambrin B from the flower ofChrysanthemum boreale . Arch. Pharm. Res. 21, 591–594 (1998). https://doi.org/10.1007/BF02975380

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  • DOI: https://doi.org/10.1007/BF02975380

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