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Saponins and flavonoid glycosides from yellow sweetclover

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Abstract

A new saponin, 3-O-[a-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl(1→2)-β-D-glucuronopyranosyl]soyasapogenol B carboxylate (6) has been isolated from the medicinal plant yellow sweetclover together with azukisaponin II(7), robinin(8), and clovin(9). 7, 8, and9 are reported for the first time from this plant. The new saponin(6) exhibited inhibitory action on leucocyte migration in inflammation.

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Literature Cited

  1. Duke, J.A.: Handbook of medicinal herbs, CRC Press, Inc., Florida, p. 305 (1985).

    Google Scholar 

  2. Kang, S.S. Lee, Y.S., and Lee, E.B.: Isolation of azukisaponin V possessing leucocyte migration inhibitory activity fromMelilotus officinalis.Kor. J. Pharmacogn. 18, 89 (1987).

    CAS  Google Scholar 

  3. Kang, S.S., Lim, C.-H., and Lee, S.Y.: Soyasapogenols B and E fromMelilotus officinalis.Arch. Pharm. Res. 19, 9 (1987).

    Article  Google Scholar 

  4. Kang, S.S. and Woo, W.S.: Melilotigenin, a new Sapogenin fromMelilotus officinalis.J. Nat. Prod. 51, 335 (1988).

    Article  CAS  Google Scholar 

  5. Kitagawa, I., Wang, H.K., Taniyama, T. and Yoshikawa, M.: Reinvestigation of the structures of soyasapogenols A, B, and E, oleanene-sapogenols from soybean, Structures of Soyasaponins I, II, and III.Chem. Pharm. Bull. 36, 153 (1988).

    CAS  Google Scholar 

  6. Kitagawa, I., Wang, H.K., Saito, M. and Yoshikawa, M.: Chemical constituents of the seeds ofVigna angularis Ohwi et Ohashi(2), azukisaponins I, II, III, and IV.Chem. Pharm. Bull. 31, 674 (1983).

    CAS  Google Scholar 

  7. Fukunaga, T., Nishiya, K., Takeya, K., and Itokawa, H.: Studies on the constituents of goat's rue.Chem. Pharm. Bull. 35, 1610 (1987).

    CAS  Google Scholar 

  8. Kitagawa, I., Wang, H.K., Saito, M., and Yoshikawa, H.: Chemical constituents of the seeds ofVigna angularis Ohwi et Ohashi(3), azukisaponins V and VI.Chem. Pharm. Bull. 31, 683 (1983).

    CAS  Google Scholar 

  9. Wenkert, E. and Gottlieb, H.E.: Carbon-13 nuclear magnetic spectroscopy of flavonoid and isoflavonoid compounds.Phytochem. 16, 1811 (1977).

    Article  CAS  Google Scholar 

  10. Nicollier, G.F. and Thompson, A.C.: Phytotoxic compounds fromMelilotus alba and isolation and identification of two new flavonoids.J. Agric. Food Chem. 30, 760 (1982).

    Article  CAS  Google Scholar 

  11. Schaufelberger, D., Gupta, M.P. and Hostettmann, K.: Flavonol and secoiridoid glycosides fromCoutoubea spicata.Phytochem.26, 2377 (1987).

    Article  CAS  Google Scholar 

  12. Ishikawa, H., Mori, Y., and Tsurufuji, S.: The characteristic feature of glucocorticoids after local application with reference to leucocyte migration and protein Exudation.Eur. J. Pharmacol. 7, 201 (1969).

    Article  PubMed  CAS  Google Scholar 

  13. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J.: Protein measurement with the folin phenol reagent.J. Biol. Chem. 193, 265 (1951).

    PubMed  CAS  Google Scholar 

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Kang, S.S., Lee, Y.S. & Lee, E.B. Saponins and flavonoid glycosides from yellow sweetclover. Arch. Pharm. Res. 11, 197–202 (1988). https://doi.org/10.1007/BF02861309

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  • DOI: https://doi.org/10.1007/BF02861309

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